Biochemist Investigating Microbial Interactions

vor 4 Wochen


Halle, Sachsen-Anhalt, Deutschland Helmholtz-Zentrum für Umweltforschung GmbH - UFZ Vollzeit

The Helmholtz Centre for Environmental Research (UFZ) is seeking a highly skilled PhD Researcher to investigate the metabolic interactions within a microbiome model system. The successful candidate will work in the Department of Molecular Toxicology, a leading research group in the field of environmental sciences.

Job Summary

The PhD Researcher will be responsible for cultivating the SIHUMIx consortium in anaerobic continuous bioreactors and manipulating specific species using the CRISP/CAS approach. The candidate will also characterize the effects of modified gene expression on the metabolomic level of the various species and the overall community metabolism using mass-spectrometry-based targeted and untargeted metabolomics and metaproteomics.

Key Responsibilities
  • Cultivate the SIHUMIx consortium in anaerobic continuous bioreactors and manipulate specific species using the CRISP/CAS approach
  • Characterize the effects of modified gene expression on the metabolomic level of the various species and the overall community metabolism using mass-spectrometry-based targeted and untargeted metabolomics and metaproteomics
  • Integrate omics-results with bioinformatic approaches and genome-based metabolic modelling to identify pathways of metabolic regulation
  • Present results at international conferences and prepare publications in peer-reviewed scientific journals
Requirements
  • M.Sc. degree in biochemistry, microbiology, bioinformatics or related fields
  • Experience in cultivating bacteria
  • Profound knowledge of microbiology and mass-spectrometry-based analysis of metabolites and proteins
  • Strong interest in bioinformatics and excellent English skills
What We Offer
  • Excellent supervision and professional qualification through our HIGRADE graduate programme
  • Freedom to master challenging tasks and opportunities to work in interdisciplinary teams
  • Integration into national and international research networks and excellent research infrastructure