Scientist for Tumor Immune Environment Analysis
vor 3 Wochen
At the German Cancer Research Center (DKFZ), we are seeking a highly motivated Scientist to join our team in the Clinical Cooperation Unit "Applied Tumor Immunity".
The successful applicant will work on cutting-edge projects and clinical trials, contributing to the deciphering of the tumor immune environment in solid cancers. The ideal candidate will have a strong background in biology, immunology, or a related field, with a focus on histology and spatial technologies.
Your Responsibilities- Design and optimize multi-marker immunohistochemistry and immunofluorescence protocols for tissues
- Oversee tissue processing, embedding, sectioning, and staining of human tissue samples
- Validate and troubleshoot existing staining protocols to ensure accuracy and reproducibility
- Design and execute experiments using spatial technologies, such as spatial transcriptomics and multiplex immunofluorescence
- Design stain-to-slide analysis workflows that drive discovery and translation of spatial biology insights to the clinic
- Perform tissue annotations and image analysis using digital pathology software, such as HALO and QuPath
- Analyze and interpret experimental data, contributing to the development of novel hypotheses
- Design experiments with internal and external partners, coordinating implementation to ensure project success
- Supervise technicians and work closely with biologists, clinicians, and computational scientists to drive translational and clinical research
- Oversee the seamless operation of the lab, including scheduling, training, supply management, and maintenance of technical infrastructure
- Maintain detailed record-keeping and required documentation
- Stay current with advancements in relevant fields, applying new techniques to ongoing projects
- Present research findings at conferences and contribute to the preparation of scientific publications and grant applications
- A PhD or Master's degree in biology, immunology, biomedical science, biomedical engineering, or a related field, with a strong emphasis on histology and spatial technologies
- Prior experience in cancer research, particularly in the tumor immune environment
- Strong analytical skills and experience with data interpretation in the context of tumor immunology
- Ability to work independently and within a multidisciplinary research environment
- Strong problem-solving skills, excellent written and verbal communication skills
- Hands-on experience with tissue processing, embedding, sectioning, and histological staining techniques
- Proficiency in spatial technologies, such as spatial transcriptomics, multiplex immunofluorescence, or similar methods
- Expertise in tissue biomarkers and an understanding of the tumor immune contexture
- Experience with digital pathology software, such as HALO and QuPath
- Knowledge of molecular biology, cell culture, or immunological assays
- Experience in writing, managing, and reviewing SOPs
- Experience in general lab management, including purchasing, stock controls, working with field service engineers, routine calibration, quality control, and waste management
- A proven track record of research publications in journals and conferences related to the position
We offer an excellent framework of state-of-the-art equipment and opportunities for international networking at the highest level. Remuneration is according to TV-L, including an occupational pension plan and capital-forming payments. We also offer 30 days of vacation per year, flexible working hours, and a possibility of mobile work and part-time work. Our Corporate Health Management Program offers a holistic approach to your well-being, and we provide access to the DKFZ International Postdoc Program and DKFZ Career Service for your personal development.
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Scientist for Tumor Immune Environment Analysis
vor 3 Wochen
Heidelberg, Baden-Württemberg, Deutschland DKFZ VollzeitScientist for Tumor Immune Environment AnalysisAt the German Cancer Research Center (DKFZ), we are seeking a highly motivated Scientist to join our team in the Clinical Cooperation Unit "Applied Tumor Immunity". As a key member of our multidisciplinary team, you will contribute to cutting-edge research projects and clinical trials focused on deciphering the...
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Scientist for Tumor Immune Environment Analysis
vor 3 Wochen
Heidelberg, Baden-Württemberg, Deutschland DKFZ VollzeitScientist for Tumor Immune Environment AnalysisAt the German Cancer Research Center (DKFZ), we are seeking a highly motivated Scientist to join our team in the Clinical Cooperation Unit "Applied Tumor Immunity". As a key member of our multidisciplinary team, you will contribute to cutting-edge research projects and clinical trials focused on deciphering the...
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Scientist for Tumor Immune Environment Analysis
vor 3 Wochen
Heidelberg, Baden-Württemberg, Deutschland Deutsches Krebsforschungszentrum (DKFZ) VollzeitJob DescriptionWe are seeking a highly motivated Scientist for the Analysis of the Tumor Immune Environment to join our dynamic multidisciplinary team at the German Cancer Research Center (DKFZ) and the National Center for Tumor Diseases Heidelberg.Key ResponsibilitiesDesign and optimize multi-marker immunohistochemistry and immunofluorescence protocols for...
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