PhD Position in Translational Cancer Immunology Researcher

vor 2 Monaten

Munich, Bayern, Deutschland LMU Klinikum Vollzeit
Research Opportunities

We are seeking a highly motivated PhD candidate to join our team at LMU Klinikum in the field of translational cancer immunology. The successful candidate will contribute to clinically oriented research that impacts patient care and treatment outcomes.

Scope of Duties
  • Antigen profiling of primary acute myeloid leukemia (AML) cells using single-cell RNA sequencing and multiparameter flow cytometry
  • Evaluation of novel T-cell bispecific antibody constructs for treatment of AML
  • Dissecting resistance mechanisms in hematologic malignancies towards bispecific antibodies and CAR-T cell therapies
  • Daily research methods:
  • Aseptic cell culture of cell lines and primary patient material
  • Isolation of peripheral blood and bone marrow mononuclear cells from patients and healthy donors
  • Cytotoxicity assays, co-cultures, immune cell activation and inhibition assays, proliferation analysis, and cytokine screening
  • Advanced flow cytometry
  • Presentation of research findings at national and international conferences
Requirements
  • Education in life sciences, biology, biochemistry, molecular biology, or related disciplines
  • Passion for impact: eager to contribute to clinically oriented research that impacts patient care and treatment outcomes
  • Driven and committed: highly motivated with a dedicated approach to research, demonstrating the ability to work independently and efficiently
  • Team player: collaborative and team-minded, thriving in a multidisciplinary research environment
  • Specialized knowledge: a strong theoretical background in immunology is a plus, and knowledge in biostatistics will be advantageous
  • Technical expertise: experience in flow cytometry and handling primary patient material is an asset
Our Offer
  • Remuneration based on the Collective Agreement for the Public Sector of the Länder (TV-L) including all allowances customary in the public sector

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