Phd Position On Inflammatory Bone Loss

vor 6 Monaten


Erlangen, Deutschland Universitätsklinikum Erlangen Vollzeit

The Department of Orofacial Orthopedics (Prof. Dr. Lina Gölz) of the Uniklinikum Erlangen in collaboration with the Department of Medicine 3 (Prof. Dr. Stefan Uderhardt) offer a PhD position in the joint project “Histocytometric and molecular assessment of the inflammatory osteoclastogenic niche in situ” within the Transregio TRR369 “Degeneration of bone induced by inflammation - DIONE”.

In our clinics, we care for patients suffering from various chronic inflammatory diseases. Pathological inflammation is often accompanied by collateral tissue destruction, e.g. bone erosion, which can lead to structural disabilities or even complete loss of function of the affected tissue in patients. The aim of this project is to understand the mechanisms that lead to emergence of bone-resorbing osteoclasts in model systems for destructive autoimmune diseases such as inflammatory arthritis and periodontitis. To this end, we will perform transcriptome profiling of immune and non-immune cells during disease progression and use state-of-the-art whole tissue optical imaging and novel AI-driven analysis techniques (3D histocytometry) to probe deep into the tissues and decipher the cellular and molecular processes behind pathological osteoclast formation in situ and in vivo as well as bone remodeling in general.

**Your tasks**:
established model systems for inducible arthritis or periodontitis
quantitative imaging combined with AI-driven analysis techniques
transcriptomic analyses

**Essential experience/ qualifications**:
**Additional advantages**:
Experience in bioinformatics, imaging techniques as well as mouse models would be advantageous

**We offer**:
A secure, interesting position as part of a motivated, open team
A well equipped lab with access to the newest technologies (e.g. light sheet microscopy, multiplex imaging, computational facilities, transcriptomics)
A motivated surrounding embedded in the Transregio TRR 369 DIONE
A thorough and qualified induction, and support in your new challenge
A structured educational PhD program (graduate school of TRR DIONE)
Varied and responsible tasks with individual opportunities to grow and develop as a professional
All public service benefits, including supplementary benefits from the Federal and State Government Pension Fund (VBL)
Pay grade is determined depending on qualifications and personal requirements according to TV-L
We seek to employ at the earliest possible starting date

Wir zählen zu den besten Krankenhäusern Deutschlands und sind einer der größten Arbeitgeber in Mittelfranken. Diesen Erfolg erarbeiten tagtäglich unsere über 9.600 hoch qualifizierten Beschäftigten in unterschiedlichsten Berufen. Wir als Uniklinikum Erlangen wissen, dass alle unsere Beschäftigten wichtig sind, damit auch in Zukunft modernste Medizin, ausgezeichnete Forschung und Patientenversorgung auf höchstem Niveau gelingen.

Wenn Sie sich eine Tätigkeit mit einem hohen sozialen Wert wünschen und die Welt der Spitzenmedizin mit uns gemeinsam gestalten und ermöglichen möchten, dann sind Sie bei uns richtig

Hinweise zu Impfungen Das UKER als Arbeitgeber

Was meinen Sie? Passen wir zu Ihnen und Sie zu uns ans Uniklinikum Erlangen?

Jetzt bewerben

Arbeiten am Puls der Medizin
Sinnvoll und systemrelevant
Berufliche Perspektiven
Vorteile eines Tarifvertrages


  • 2 Phd Positions

    vor 7 Monaten


    Erlangen, Deutschland Universitätsklinikum Erlangen Vollzeit

    The Department of Medicine 3 (Prof. Dr. Stefan Uderhardt) and the Department of Orofacial Orthopedics (Prof. Dr. Lina Gölz) offer 2 PhD positions in the joint project “Histocytometric and molecular assessment of the inflammatory osteoclastogenic niche in situ” within the Transregio TRR369 “Degeneration of bone induced by inflammation - DIONE”. In...

  • Phd Student

    vor 6 Monaten


    Erlangen, Deutschland Universitätsklinikum Erlangen Vollzeit

    State-of-the-art medicine and care - with safety! Since its foundation in 1815, the University Hospital Erlangen has offered medicine at the highest level. The latest findings in medical research and state-of-the-art equipment are used in diagnosis and therapy. More than 9,400 employees from around 50 professions are needed to fulfil the diverse tasks of...

  • Bioinformatician Phd

    vor 2 Wochen


    Erlangen, Deutschland Universitätsklinikum Erlangen Vollzeit

    Medicine 3 is dedicated to improving patients’ quality of life and curing chronic inflammatory and autoimmune diseases through a holistic approach, cutting-edge diagnostics, and a commitment to research, teaching, and training. The Department of Stem Cell Biology focuses on modeling nervous system diseases using patient-specific stem cell models. By...


  • Erlangen, Deutschland Universitätsklinikum Erlangen Vollzeit

    State-of-the-art medicine and nursing care you can rely on! - Since being founded in 1815, Universitätsklinikum Erlangen has offered medicine of the highest standard and incorporated the latest insights from medical research and state-of-the-art equipment into diagnosis and therapy. More than 9.500 employees from approximately 50 different occupations are...


  • Erlangen, Deutschland Universitätsklinikum Erlangen Vollzeit

    State-of-the-art medicine and nursing care you can rely on! - Since being founded in 1815, Universitätsklinikum Erlangen has offered medicine of the highest standard and incorporated the latest insights from medical research and state-of-the-art equipment into diagnosis and therapy. More than 9.500 employees from approximately 50 different occupations are...


  • Erlangen, Deutschland Universitätsklinikum Erlangen Vollzeit

    State-of-the-art medicine and nursing care you can rely on! - Since being founded in 1815, Universitätsklinikum Erlangen has offered medicine of the highest standard and incorporated the latest insights from medical research and state-of-the-art equipment into diagnosis and therapy. More than 9.600 employees from approximately 50 different occupations are...

  • Phd Position

    vor 2 Monaten


    Erlangen, Deutschland Friedrich-Alexander-Universität Erlangen-Nürnberg Vollzeit

    Your workplace Our benefits - 30 days annual leave at five working days per week with additional free days on December 24 and 31 - Pleasant work environment - Diverse opportunities for further education and training - Personal development opportunities - Collegial and supportive working atmosphere - Joint team activities - Discounted meals in our canteens -...

  • Research Fellow

    vor 2 Monaten


    Erlangen, Deutschland Friedrich-Alexander-Universität Erlangen-Nürnberg Vollzeit

    **Das Aufgabengebiet umfasst u. a.**: Area of responsibility About the School Engaging with multiplicity is essential for understanding 21st-century social worlds, which are invariably constituted through the interaction of multiple social realities, lifeworlds, world views, approaches to future-making, and forms of knowledge (making). All the major problems...


  • Erlangen, Deutschland Universitätsklinikum Erlangen Vollzeit

    Group of translational tumor immunology, Institute of Pathology. **Short Project description**: Muscle-invasive (MIBC) and metastatic urothelial cancer (mUC) are an aggressive type of cancer for which overall survival rates have shown little improvement over the past few decades despite promising therapeutic advances such as immunotherapy. We previously...


  • Erlangen, Deutschland Universitätsklinikum Erlangen Vollzeit

    This position will be located in the study group of Musculoskeletal Function and Mechanobiology. Research in this study group focuses on the role of musculoskeletal function in patient cohorts and healthy individuals. We have a special interest in the role of immobility for musculoskeletal health which we investigate in space flight related studies and...


  • Erlangen, Deutschland Universitätsklinikum Erlangen Vollzeit

    State-of-the-art medicine and nursing care you can rely on Since being founded in 1815, Universitätsklinikum Erlangen has offered medicine of the highest standard and incorporated the latest insights from medical research and state-of-the-art equipment into diagnosis and therapy. More than 7,500 employees from approximately 50 different occupations are...

  • PhD Student

    vor 4 Wochen


    Erlangen, Deutschland Friedrich-Alexander-Universität Erlangen-Nürnberg - Karriere Vollzeit

    GeoZentrum Nordbayern, Lehrstuhl für Endogene Geodynamik offersIhre AufgabenWe are welcoming applications for a PhD position in the DFG-ANR funded project “Hydrothermal Economic Resources in Magmatic EnvironmentS (HERMES)”. The PhD candidate will be part of an interdisciplinary working group focusing on geochemistry, magmatic petrology and...

  • 3 PhD positions

    vor 7 Monaten


    Erlangen, Deutschland Friedrich-Alexander-Universität Erlangen-Nürnberg Vollzeit

    Qualifikationen : We are looking for excellent candidates with interest in the areas of theoretical, statistical, mathematical and bio-physics, or applied mathematics and computer science with strong interest in biology and who enjoy interdisciplinary work. Stellenzusatz Befristetes Forschungsvorhaben To apply: Send a cover letter, curriculum vitae, list...


  • Erlangen, Deutschland Friedrich-Alexander-Universität Erlangen-Nürnberg - Karriere Vollzeit

    Das Institut für Geographie der Universität Erlangen-Nürnberg sucht PhD position in UAV-based glacier monitoring and boundary layer research at FAU (Germany) (1.3.2025) (AG A. Groos).Ihre AufgabenWithin the framework of the newly funded Franco-German research project FlyHigh, the Institute of Geography at the Friedrich-Alexander-Universität...


  • Erlangen, Deutschland Friedrich-Alexander-Universität Erlangen-Nürnberg Vollzeit

    Qualifikationen : We expect flexibility and commitment, but also communication skills and the capability to work in a team. For application as a PhD student, a diploma or master degree in chemistry, physics, chemical engineering, or materials science is required. Specific experience in the research field is not mandatory. Stellenzusatz The...


  • Erlangen, Deutschland Friedrich-Alexander-Universität Erlangen-Nürnberg Vollzeit

    **Das Aufgabengebiet umfasst u. a.**: - Fieldwork and sampling of magmatic rocks related to porphyry-epithermal systems in NE Greece - Geochemical and geochronological study of magmatic rocks and accessory minerals - Investigating the ore-forming potential of magmas in a tightly constrained chronological context during arc migration - Studying the links...


  • Erlangen, Deutschland Forschungszentrum Jülich GmbH Vollzeit

    Would you like to contribute to the energy transition in Germany through your work? Then the Helmholtz Institute Erlangen-Nürnberg (for Renewable Energy) (HI ERN) is the right place for you! The HI ERN forms the core of the close partnership between Forschungszentrum Jülich, Helmholtz-Zentrum Berlin for Materials and Energy, and...


  • Erlangen, Deutschland Friedrich-Alexander-Universität Erlangen-Nürnberg - Karriere Vollzeit

    The Chair of Experimental Physics at Friedrich-Alexander-Univeristät Erlangen-Nürnberg (FAU) invites applications forIhre AufgabenWe are seeking highly motivated PhD candidates to join a rapidly growing research team, led by Christopher Eichler, which conducts state-of-the-art experimental research in quantum computing, quantum information science and...


  • Erlangen, Deutschland Universitätsklinikum Erlangen Vollzeit

    State-of-the-art medicine and nursing care you can rely on! - Since being founded in 1815, Universitätsklinikum Erlangen has offered medicine of the highest standard and incorporated the latest insights from medical research and state-of-the-art equipment into diagnosis and therapy. More than 9.600 employees from approximately 50 different occupations are...


  • Erlangen, Deutschland Friedrich-Alexander-Universität Erlangen-Nürnberg Vollzeit

    Your workplace The research group Sustainability Transition Policy works at the Friedrich-Alexander University Erlangen-Nuremberg within the Faculty of Law, Business, and Economics. Our group conducts problem-oriented, interdisciplinary research on policies and strategies for the transition to climate neutrality in Germany, Europe, and globally. Our...