Phd Student

vor 5 Monaten


Erlangen, Deutschland Universitätsklinikum Erlangen Vollzeit

State-of-the-art medicine and care - with safety Since its foundation in 1815, the University Hospital Erlangen has offered medicine at the highest level. The latest findings in medical research and state-of-the-art equipment are used in diagnosis and therapy. More than 9,400 employees from around 50 professions are needed to fulfil the diverse tasks of Erlangen University Hospital and care for our patients around the clock.

**Your tasks**:
This project is part of TRR 374 “Tubular system and interstitium of the kidney: (Patho-) physiology and crosstalk” and aims to investigate the role and interaction of uromodulin (UMOD), neutrophil extracellular traps (NET) and the complement system in inflammatory and non-inflammatory tubulointerstitial kidney disease. To this end, we will investigate the presence, abundance and interaction of these three factors and their effects on inflammatory processes, fibrosis and renal function in human kidney biopsies, animal and in vitro models. Using inhibitor and knockout strategies, we will assess whether modulation of UMOD-NET-complement interaction could represent a new therapeutic target in tubulointerstitial kidney disease.

**Comments**:
Intended pay grade depending on qualifications and personal
requirements according to TV-L
The position is for a fixed term of up to 36 month

**Essential experience/qualifications**:
M. Sc. in a natural science degree programme
Highly motivated and enthusiasm for research
Willingness to work with animals

**Additionally beneficial are**:
Experience with in vivo models (Felasa B) and/or cell culture would be advantageous

**We offer**:
We offer an interesting workplace to carry out a scientific doctoral thesis in a motivated, open-minded team and integration into a DFG-funded research network (TRR 374). This provides excellent networking opportunities with other scientists and a special training programme for PhD students.

Wir zählen zu den besten Krankenhäusern Deutschlands und sind einer der größten Arbeitgeber in Mittelfranken. Diesen Erfolg erarbeiten tagtäglich unsere über 9.600 hoch qualifizierten Beschäftigten in unterschiedlichsten Berufen. Wir als Uniklinikum Erlangen wissen, dass alle unsere Beschäftigten wichtig sind, damit auch in Zukunft modernste Medizin, ausgezeichnete Forschung und Patientenversorgung auf höchstem Niveau gelingen.

Wenn Sie sich eine Tätigkeit mit einem hohen sozialen Wert wünschen und die Welt der Spitzenmedizin mit uns gemeinsam gestalten und ermöglichen möchten, dann sind Sie bei uns richtig

Hinweise zu Impfungen Das UKER als Arbeitgeber

Was meinen Sie? Passen wir zu Ihnen und Sie zu uns ans Uniklinikum Erlangen?

Jetzt bewerben

Arbeiten am Puls der Medizin
Sinnvoll und systemrelevant
Berufliche Perspektiven
Vorteile eines Tarifvertrages



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