Scientist Iii, R&d
vor 4 Monaten
Asklepios BioPharmaceutical, Inc. (AskBio) is a leading, clinical-stage gene therapy company founded in 2001 based on the work of adeno-associated virus (AAV) gene therapy visionary and pioneer, Jude Samulski, PhD. Since that time, our commitment to developing life-saving medicines that can potentially cure genetic diseases has never wavered.
At AskBio, we’ve built a foundation of therapeutic programs, AAV manufacturing and a rich portfolio of patented technology. Our therapeutic focus includes neuromuscular, central nervous system, cardiovascular and metabolic diseases with clinical trials underway for Pompe disease, Parkinson’s disease, and congestive heart failure. Our gene therapy platform includes Pro10, an industry-leading proprietary cell line manufacturing process, and an extensive AAV capsid and promoter library.
We became a wholly-owned, independently operated, subsidiary of Bayer AG in late 2020 as a cornerstone of its newly formed Cell & Gene Therapy (CGT) platform. Our global headquarters is in Research Triangle Park, NC. Additionally, we have significant operations in Philadelphia, PA, Columbus, OH, Scotland, France, and Spain.
Our vision: Pioneering science to create transformative molecular medicines.
Our mission: Lead innovative science and drive clinical outcomes to transform people's lives.
Our principles:
- Advance innovative science by pushing boundaries.- Bring transformative therapeutics to patients in need.- Provide an environment for employees to reach their fullest potential.
Our values:
- Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.- Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.- Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.- Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.- Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.
The Scientist III, R&D at AskBio GmbH will be one of the key members to support the development of rAAV gene therapy with highly complex novel technologies. The scientist has responsibility for analysis of DNA, RNA, and protein expression from tissues and cell lines. Target disease indications include heart, CNS, neuromuscular, liver systemic and liver metabolic diseases innovative approaches to improve AAV capsid development and understanding of underlying AAV biology. New technologies will be used for understanding viral-host interactions. The Scientist actively participate as a member of multifunctional project teams, executing projects from concept to implementation.
**Responsibilities**:
- Lead and perform “hands-on” work in selecting complex AAV-capsid libraries.
- Design experiments and use statistical tools to analyse various data sets and types.
- Develop robust, efficient, scalable strategies for improving AAV capsid developments in collaboration with fellow scientists, external collaborators, and upper management.
- Prepare internally reviewed technical reports, development reports, manuscripts, and deliver internal and external oral presentations.
- Conduct experiments as part of a variety of research and development activities. e.g. small-scale studies, scale up studies, technology transfer and process improvements.
- Actively participate as a member of multifunctional project teams, executing projects from concept to implementation.
- Evaluate and summarize experimental results, develop and test hypotheses to improve understanding AAV capsid selection strategies.
Required Education and Experience
- Master’s degree in Immunology, Biology, Biochemistry, Biotechnology, Virology or a related field
- PhD in a scientific discipline.
- 5-8 years of related experience mainly virology.
- Seen as an internal “go to” for more junior employees who are seeking coaching and direction on highly complex technical issues.
- Expert knowledge in designing, implementing, and troubleshooting experiments.
- Must be able to generate high quality data for presentations and publications.
- Excellent interpersonal skills with the ability to interact effectively with teams, internally and externally.
- Proven ability to work in a fast-paced environment, meet deadlines, & prioritize work on multiple projects. Strong attention to detail with the ability to handle multiple responsibilities simultaneously.
- Acts independently to define new assignments that generates innovative methods and procedures.
- Ability to independently integrate and develop research programs that align with the goals of the company as defined by senior management.
- Contribute to techni
-
Senior Data Scientist
vor 4 Monaten
Heidelberg, Deutschland Orbis Vollzeit**Location: Heidelberg, Baden-Württemberg, Germany**: **Salary: Competitive Salary**: **Permanent**: **Titel - Senior Data Scientist** **Standort - Heidelberg oder Berlin** **Flexibilität - Hybrid** **Über das Unternehmen** Sie sind ein führendes deutsches datengetriebenes Softwareunternehmen, das für seine Kultur bekannt ist und in den drei...
-
Data Scientist
vor 2 Wochen
Heidelberg, Baden-Württemberg, Deutschland paretos GmbH VollzeitAbout paretos GmbHparetos GmbH is a leading provider of AI-based decision intelligence solutions for businesses. Our mission is to empower organizations to make data-driven decisions and drive growth through innovative technology.Job SummaryWe are seeking a highly skilled Data Scientist to join our team at paretos GmbH. As a Data Scientist, you will play a...
-
Data Scientist
vor 2 Wochen
Heidelberg, Baden-Württemberg, Deutschland paretos GmbH VollzeitAbout paretos GmbHparetos GmbH is a leading provider of AI-based decision intelligence solutions for businesses. Our mission is to empower organizations to make data-driven decisions and drive growth through innovative technology.Job SummaryWe are seeking a highly skilled Data Scientist to join our team at paretos GmbH. As a Data Scientist, you will play a...
-
Associate Liaison Scientist R&d
vor 4 Monaten
Heidelberg, Deutschland Octapharma VollzeitJob ID: 56736- Location: Heidelberg, DE- Job Level: Entry Level- Job Category: International Early Career Program- Employment Type: Permanent position- Career Level: Octapharma Biopharmaceuticals GmbH a subsidiary of the Octapharma group founded in 1997 is a successful and expanding biotech company in Heidelberg. Our core business is the development of...
-
Senior Data Scientist
vor 4 Monaten
Heidelberg, Deutschland HMS Analytical Software Vollzeit**Senior Data Scientist (mwd)**: **Berufserfahrene** *** *** **Heidelberg, Berlin, Remote** *** *** **Data Scientist** *** *** **Vollzeit, Teilzeit (mind. 80%)** *** *** **Ihre** Aufgaben**: - Als Senior Data Scientist (mwd) wirken Sie u.a. aktiv bei der Digitalisierung von Geschäftsprozessen und Produktionsanlagen durch künstliche Intelligenz...
-
Research Scientist
vor 1 Woche
Heidelberg, Baden-Württemberg, Deutschland Octapharma VollzeitAbout OctapharmaWe are a leading global biopharmaceutical company dedicated to the development and production of human protein products. Our mission is to provide innovative treatments for patients worldwide.Our R&D SitesWe have seven state-of-the-art R&D sites across Europe and the US, where our expert teams work tirelessly to develop new treatments and...
-
Research Scientist
vor 1 Woche
Heidelberg, Baden-Württemberg, Deutschland Octapharma VollzeitAbout OctapharmaWe are a leading global biopharmaceutical company dedicated to the development and production of human protein products. Our mission is to provide innovative treatments for patients worldwide.Our R&D SitesWe have seven state-of-the-art R&D sites across Europe and the US, where our expert teams work tirelessly to develop new treatments and...
-
Heidelberg, Baden-Württemberg, Deutschland DKFZ VollzeitJob DescriptionWe are seeking a highly skilled Data Scientist to join our team at the German Cancer Research Center (DKFZ) in Heidelberg. As a Data Scientist in Cancer Genomics and Epigenomics, you will play a key role in developing and implementing computational methods and workflows to analyze genomic and epigenomic data in the context of childhood...
-
Heidelberg, Baden-Württemberg, Deutschland DKFZ VollzeitJob DescriptionWe are seeking a highly skilled Data Scientist to join our team at the German Cancer Research Center (DKFZ) in Heidelberg. As a Data Scientist in Cancer Genomics and Epigenomics, you will play a key role in developing and implementing computational methods and workflows to analyze genomic and epigenomic data in the context of childhood...
-
Research Scientist
vor 3 Monaten
Heidelberg, Deutschland Reckitt VollzeitHome to the world's best loved and trusted hygiene, health, and nutrition brands. Our purpose defines why we exist: to protect, heal and nurture in the relentless pursuit of a cleaner, healthier world. We are a global team united by this purpose. Join us in our fight to make access to the highest quality hygiene, wellness, and nourishment a right and not a...
-
Scientist (m/f/d) Automation and Data Management
vor 2 Monaten
Heidelberg, Deutschland Octapharma VollzeitScientist (m/f/d) Automation and Data Management Job ID: 58164 Location: Heidelberg, DE Job Level: Entry Level Job Category: Research and Development Employment Type: Permanent position Career Level: About OctapharmaHeadquartered in Lachen, Switzerland, Octapharma is one of the largest human protein manufacturers in the world, developing and producing...
-
Lab Research Scientist Development, Development
Vor 6 Tagen
Heidelberg, Deutschland Reckitt VollzeitHome to the world's best loved and trusted hygiene, health, and nutrition brands. Our purpose defines why we exist: to protect, heal and nurture in the relentless pursuit of a cleaner, healthier world. We are a global team united by this purpose. Join us in our fight to make access to the highest quality hygiene, wellness, and nourishment a right and not a...
-
Scientist Product Development Beverage
vor 2 Monaten
Heidelberg, Deutschland Archer Daniels Midland Company Vollzeit**Scientist Product Development Beverage**: Heidelberg Germany Research & Development **Scientist Product Development Beverage (M/F/d)** **In the CD&D Team in Heidelberg/Germany** **Your Role** - You develop innovative concepts and recipes for semi-finished and finished products for our national and international customers in the beverage sector - You...
-
Heidelberg, Baden-Württemberg, Deutschland DKFZ VollzeitData Scientist in Cancer Genomics and EpigenomicsWe are seeking a highly motivated and skilled Data Scientist to join our team at the German Cancer Research Center (DKFZ) in Heidelberg. As a key member of our Clinical Bioinformatics – Translational Genomics group, you will play a crucial role in developing computational methods and workflows to answer...
-
Heidelberg, Baden-Württemberg, Deutschland DKFZ VollzeitData Scientist in Cancer Genomics and EpigenomicsWe are seeking a highly motivated and skilled Data Scientist to join our team at the German Cancer Research Center (DKFZ) in Heidelberg. As a key member of our Clinical Bioinformatics – Translational Genomics group, you will play a crucial role in developing computational methods and workflows to answer...
-
Postdoctoral scientist, part-time
vor 4 Wochen
Heidelberg, Deutschland Deutsches Krebsforschungszentrum DKFZ VollzeitResearch for a life without cancer“ is our mission at the German Cancer Research Center. Every contribution counts – whether in research, administration or infrastructure. Within the "DKFZ-Hector Cancer Institute at the University Medical Center Mannheim", we are looking for the Division of Personalized Medical Oncology (headed by Prof. The DKFZ-Hector...
-
Postdoctoral scientist, part-time
vor 3 Wochen
Heidelberg, Deutschland Deutsches Krebsforschungszentrum (DKFZ) VollzeitWithin the "DKFZ-Hector Cancer Institute at the University Medical Center Mannheim", we are looking for the Division of Personalized Medical Oncology (headed by Prof. Full-time Personalized Medical Oncology The DKFZ-Hector Cancer Institute was established as a partnership between the German Cancer Research Center (DKFZ), the University Hospital Mannheim...
-
Senior Scientist in Personalized Oncology
vor 4 Wochen
Heidelberg, Deutschland Deutsches Krebsforschungszentrum DKFZ Vollzeit„Research for a life without cancer“ is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts...
-
Senior Scientist in Personalized Oncology
vor 4 Wochen
Heidelberg, Deutschland Deutsches Krebsforschungszentrum DKFZ Vollzeit„Research for a life without cancer“ is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention strategies. We develop new methods with which tumors can be diagnosed more precisely and cancer patients can be treated more successfully. Every contribution counts...
-
Senior Scientist in Personalized Oncology
vor 3 Wochen
Heidelberg, Deutschland DKFZ VollzeitSenior Scientist in Personalized Oncology Reference number: 2024-0269 Heidelberg Full-time Personalized Medical Oncology “Research for a life without cancer" is our mission at the German Cancer Research Center. We investigate how cancer develops, identify cancer risk factors and look for new cancer prevention...
