Masterthesis: Pharmaceutical Development Biologicals
vor 2 Monaten
**The Position**:
Are you looking for an exciting challenge during your studies in an internationally successful company that has been awarded as one of the “Global Top Employers” several times? Do you want to apply, deepen, and expand your acquired knowledge in practice?
As the world leader in the production of innovative medicines, we at Boehringer Ingelheim offer you the opportunity to get to know the many tasks of the Pharmaceutical Development Biologicals department.
Biotherapeutic drug products are typically formulated as liquid dosage forms. In formulations that contain protein, surfactants are often necessary to ensure the protein's stability throughout the drug product's shelf life. Non-ionic surfactants are frequently employed as functional excipients for this purpose. The objective of the master's thesis is to assess the influence of different types and qualities of these surfactants on the stability of the drug product. Additionally, the task involves evaluating potential correlations between the material attributes of the drug, such as antibodies, and the surfactant being tested.
***Tasks and Responsibilities**:
- Planning and conducting stability studies for assessing the colloidal or thermal stability of proteins in surfactant-containing formulations
- Determination of protein integrity using different orthogonal methods, such as e. g. High-Performance Liquid Chromatography (HPLC)
- Characterization and quantification of surfactants via Liquid Chromatography-Mass Spectrometry (LC-MS)-based methods
- Usage of different compendial methods for the detection of sub-visible and visible particles such as Micro-flow Imaging (MFI)
- Statistical data evaluation Furthermore, you get to know the everyday working routine and the mindset in one of the pharmaceutical industry's top 20 companies
**Your Profile**:
- Currently pursuing master's degree in Biotechnology, Biochemistry, or related study field
- High affinity to laboratory work (practical experience desirable)
- High interest in agile mindset, methods and tools
- Independent and structured working style
- Proficient use of MS Office
- Fundamental programming skills in R or Python would be of advantage Excellent communication and writing skills in English and German
**What we can offer you**:
- During your thesis you will receive an allowance of 900€ per month In our team you have a flexible time model during which you can write your final thesis.
The duration of the internship is **9-12 months **( **3-6-months **internship + **6 months **master thesis). The start date is in **July 2024.**
**Ready to contact us?**:
Please contact our HR Direct Team, Tel: +49 (0) 6132 77-3330.
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