4 Phd Positions for Life Scientists

Vor 3 Tagen


Freiburg, Deutschland Universitätsklinikum Freiburg Vollzeit

The Institute for Surgical Pathology, University Medical Center Freiburg, Germany is offering

**4 PhD positions for life scientists (M/F/d)**:

- The research at the Institute for Surgical Pathology is highly interdisciplinary and has a strong focus on translational research in oncology and nephrology. In addition, research includes cutting-edge methodological developments in the areas of shotgun proteomics, spatial proteomics and metabolomics, organotypic in vitro cultures and artificial intelligence for image analysis.

**We offer 4 PhD positions in the following areas**:
**1 Role of matrisomal biology for heterocellular crosstalk in kidney cancer - Prof. Christoph Schell**
This position uses multiplex immunostaining, organotypic tissue slice cultures and CRISPR/Cas9 modified cellular models to dissect the role of matrisomal biology in modulating heterocellular crosstalk in the tumor microenvironment of renal cell carcinoma.

**2 Spatial profiling of kidney cancer - Prof. Oliver Schilling**
This position includes technical developments in the areas of mass spectrometry based spatial proteomics (LC-MS/MS and MALDI imaging) as well as degradomic approaches in the context of kidney cancer.

**3 Spatial multi-omics and organotypic cultures of bile duct cancer - Dr. Melanie Föll**
This position combines spatial metabolomics by MALDI imaging with spatial proteomics by LC-MS/MS applied to bile duct cancer and follow up on novel therapeutic approaches using in vitro organotypic tissue slice cultures.

**4 Proteomics based personalized medicine for glioblastoma - Prof. Oliver Schilling**
- This position develops and applies high-throughput shotgun proteomics to identify novel therapeutic targets and stratify glioblastoma patients for personalized therapies.
- The laboratories of Prof. Schell, Prof. Schilling and Dr. Föll work closely together and offer a friendly and supportive work environment with extensive in-house and external training for scientific and professional development. We offer modern and well-equipped laboratories including cutting edge mass spectrometry instrumentation (timsTOF fleX). Our interdisciplinary groups work in close exchange with local and international partners. All projects provide ample opportunities for scientific publishing and conference participation.
- All positions are according to TV-L (65 %), with a starting date between January and April. The duration of the positions is 3 to 4 years.

**Contacts for further inquiries**:
**Prof. Oliver Schilling**

**Prof. Christoph Schell**

**Dr. Melanie Föll**

Allgemeiner Hinweis: Die Vergütung erfolgt nach Tarif. Vollzeitstellen sind grundsätzlich teilbar, soweit dienstliche oder rechtliche Gründe nicht entgegenstehen. Schwerbehinderte Bewerber*innen werden bei gleicher Eignung besonders berücksichtigt. Einstellungen erfolgen durch die Abteilung Personalbetreuung.


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