Research Assistant

vor 4 Monaten

Heidelberg, Deutschland BioMed X GmbH Vollzeit

**About BioMed X**:
BioMed X is an independent research institute with sites in Heidelberg, Germany, New Haven, Connecticut, XSeed Labs in Ridgefield, Connecticut, and a worldwide network of partner locations. Together with our partners, we identify big biomedical research challenges and provide creative solutions by combining global crowdsourcing with local incubation of the world’s brightest early-career research talents. Each of the highly diverse research teams at BioMed X has access to state-of-the-art research infrastructure and is continuously guided by experienced mentors from academia and industry. At BioMed X, we combine the best of two worlds - academia and industry - and enable breakthrough innovation by making biomedical research more efficient, more agile, and more fun.

**About the Team**:
The group, led by Dr. Semih C. AKINCILAR, is dedicated to unravelling the mechanisms by which cancer cells evade immune surveillance and devising innovative strategies to convert cold tumor microenvironments into hot ones. To achieve this goal, the team utilizes state-of-the-art single-cell sequencing techniques to pinpoint non-immunogenic tumor clusters. Their primary focus centers on investigating DNA damage and DNA sensing pathways in order to develop patient-specific therapies.

**The Position**:
**Required skills**:

- Expertise in molecular and cellular biology assays (vector design, cloning, protein/gene expression analyses, immunoprecipitation, and gene manipulation techniques, etc.)
- Experience in immunological assays (flow cytometry, immunofluorescence, cell sorting, histology, Elisa/Luminex etc.)
- Demonstrated ability to work with patient samples and mouse models
- Independent thinking and motivated to learn new laboratory techniques
- Experienced to work in interdisciplinary teams
- Excellent communication skills in English

**Additional preferred skills**:

- Experience in solid tumors, especially CRC
- Experience in DNA damage and DNA sensing pathways
- Prior experience with complex ex vivo models

**What we offer**:
The post is offered for a limited term until 31 January 2029.
- International, diverse, and positive work atmosphere, flexible working environment
- A competitive salary
- Access to training and lecture courses in house as well as in neighboring research institutions on the Life Science Campus in Heidelberg
- Access to a vast network in science and industry.
- Job ticket, sponsored fitness contract, complimentary fresh fruit, soft drinks and chocolate team recognition events, etc.

The position is sponsored by **Merck KGaA**.**.
- 1-page cover letter explaining the reasons of interest to join our team
- Curriculum Vitae outlining scientific interests, research achievements, a record of publications, future personal goals and extra-scientific passions
- 2 reference letters

**Contact**:
**BioMed X Institute**

Im Neuenheimer Feld 515
69120 Heidelberg
Germany

**Contact: Dr. Semih Akincilar**
**Phone**: +49 6221 42611 0

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