Postdoctoral Researcher

**Department**: Department of Dermatology

**Location**: University Hospital Düsseldorf, Medical Faculty, Heinrich-Heine-University, Düsseldorf,
Germany

**Position Type**: Postdoctoral Researcher

**About Us**: The Department of Dermatology at the University Hospital Düsseldorf is a globally
recognized Center for Advanced Research in skin diseases. Our state-of-the-art program
encompasses a variety of projects including the study of the molecular drivers of chronic inflammatory
skin diseases, the neuro-immune communication and microbe-host interactions. We use state-of-the
- art OMICs techniques and in-house bioinformatics combined with in vitro
- and in vivo-models with the
goal to translate basic science findings into clinical use.

**Overview of active projects**:

- DFG-RU2690 PruSEARCH: Unraveling pruritus pathways in chronic inflammatory skin diseases
- EU-BIOMAP (No 821511)**: Investigating cutaneous microbe-host interactions
- DFG-RU5489 Investigating the ambiguous ways of the aryl hydrocarbon receptor (AHR)
signalling in skin diseases: The AHR as a target for microbe-host interaction
- EU-SKINDEV (Skin microbial devices; No 101098826): Designing genetically modified probiotic

organisms to treat atopic skin inflammation****:

- DFG-HO 2092/8-1: Epidermal growth factor signaling controls skin barrier function and the
- cutaneous microbiome
- FOKO 2023-40: Precision-cut skin slices as a novel tool for precision medicine in patients with

refractory/therapy-resistant psoriatic inflammation

**Position Summary**: We are seeking a dedicated and skilled Postdoctoral Researcher with a focus in
in advancing our research, employing in vitro
- and in vivo-models together with state of the art OMICs
and imaging technologies.

**Key Responsibilities**:

- Conducting high-level research within the scope of our projects.
- Experiment design, implementation, data collection, and analysis.
- Perform various omics technologies and laboratory techniques.
- Supervision of PhD and MD students
- Collaboration with a team of bioinformaticians, wet lab researchers and clinicians.
- Contributing to the writing of research papers and grant proposals.
- Presenting research findings at workshops and conferences.
- Participates in collaboration with other biological and clinician scientists throughout the
- academic community.
- Helps develop laboratory culture of urgency and scientific excellence with a focus on therapeutic

impact.

**Qualifications**:

- PhD in Biology, Molecular (Cell) Biology, Biochemistry, Biomedical Sciences, or related field.
- Extensive experience in laboratory research, preferably in dermatology or related areas.
- Expert in western blotting, ELISA, qPCR, FACS, and cell culture.
- Proficiency in OMICs technologies and data analysis.
- Substantialexperience in cellular and molecular immunology methods.
- Knowledge on, or experience in working on cutaneous microbiome, with special regards to
- Cutibacterium_ _acnes_ and _Staphylococcus aureus_.
- Exceptional scientific background, strong publication record in peer-reviewed journals and a
- track-record of problem-solving and delivery.
- Excellent communication and organizational skills with close attention to details and strong time
- management skills.
- Strong ability to work independently and as part of a team.
- Collaborative mindset - strong teamworking capabilities, proactive in helping the team succeed,
- and takes ownership of team-based tasks
- Proficiency in English language. Excellent written and verbal communication skills.
- Rapid learning and understanding skills in the following fields: organic chemistry, medicinal

chemistry, molecular design, pharmacokinetics, patent preparation and prosecution.

**We Offer**:

- A dynamic and international research environment.
- Opportunities for professional growth and collaboration with leading experts.
- Access to state-of-the-art facilities and resources.
- Competitive salary.

**Salary range**: income is determined within the TV-L E13 salary group. The Employment contract will
be with the University of Duesseldorf.

The University of Duesseldorf is committed to equal opportunities and diversity. Women are especially
with disabilities / special needs or of equal status (SGB IX).

The employment is initially limited to a period of 3 years, with the option of extension. These are
qualification positions within the meaning of the Act of Academic Fixed-Term Contract
(Wissenschaftszeitvertragsgesetz - WissZeitVG as per - 2 para. 1).

research interests and experience, copies of relevant publications, and the contact details of at least
two referees.

**Application Deadline**: September 1st, 2024

**Contact Information**:
Univ.Prof. Dr. Bernhard Homey
Dept. of Dermatology, University Hospital Düsseldorf, Medical Faculty, Heinrich-Heine-University
Düsseldorf

The University Hospital Düsseldorf is an equal opportunity employer and strongly encourages