Postdoctoral Scientist for Liquid Biopsy of Cancer
vor 2 Wochen
**Position**:Postdoctoral Scientist for Liquid Biopsy of Cancer**
**Department**: Cancer Genome Research
**Code number**:2024-0062
The German Cancer Research Center is the largest biomedical research institution in Germany. With more than 3,000 employees, we operate an extensive scientific program in the field of cancer research.
The Division of Cancer Genome Research at DKFZ has a strong background in the analysis of genomic and epigenomic alterations in circulating DNA (cfDNA) and RNA from cancer patients (Angeles et al, 2022, 2023; Janke et al., 2022). In collaboration with partners at DKFZ, Heidelberg University and abroad, we use a broad spectrum of genomics and proteomics technologies to monitor tumor progression in samples from clinical studies.
To strengthen our team, we are looking for a postdoctoral scientist starting in April 2024.
**Job description**:
The division is a partner in several BMBF-funded cooperation projects investigating tumor heterogeneity in space and time. Our role in these projects is the systematic analysis of longitudinal liquid biopsies (plasma) to monitor tumor heterogeneity and subclonal composition over time using state-of-the-art genomic and proteomic technologies.
**References**:
Angeles AK, Janke F, Daum AK, Reck M, Schneider MA, Thomas N, Christopoulos P, Sültmann H. Integrated circulating tumor DNA and cytokine analysis for therapy monitoring of ALK-rearranged lung adenocarcinoma. Brit J Cancer 129(1):112-121; Apr 29. doi: 10.1038/s41416-023-02284-0, 2023
Janke F, Angeles AK, Riediger AL, Bauer S, Reck M, Schneider MA, Muley T, Thomas M, Christopoulos P, Sültmann H. Monitoring progression of ALK-rearranged lung adenocarcinoma using DNA methylation patterns in cell free DNA. Clinical Epigenetics, 14(1):163; doi: 10.1186/s13148-022-01387-4, 2022
Angeles AK*, Christopoulos P*, Yuan Z, Bauer S, Janke F, Ogrodnik SJ, Reck M, Schlesner M, Meister M, Schneider MA, Dietz S, Stenzinger A, Thomas M, Sültmann H. Early identification of disease progression in ALK-rearranged lung cancer using circulating tumor DNA analysis. NPJ Precision Oncology, 5(1):100; DOI 10.1038/s41698-021-00239-3, 2021
**Requirements**:
- PhD in biology, biochemistry, bioinformatics or related fields
- Interest in performing translational research using state-of-the-art technologies
- Top level command of written and spoken English
- Highly motivated team player with excellent communication skills
**We offer**:
- Interesting, versatile workplace
- Excellent framework conditions: state-of-the-art equipment and opportunity for international networking at the highest level
- Remuneration according to TV-L incl. occupational pension plan for the public service and capital-forming payments
- 30 days of vacation per year
- Flexible working hours
- Possibility of mobile work and part-time work
- Family-friendly working environment, including parent-child room, counseling services, e.g. on Elder Care
- Sustainable travel to work: subsidized Germany job ticket
- Develop your full potential: access to the DKFZ International Postdoc Program and DKFZ Career Service with targeted offers for your personal development to further develop your talents
- Our Corporate Health Management Program offers a holistic approach to your well-being
**Important notice**:
**Earliest possible start date**: 01.04.2024
**Duration**:The position is initially limited to 2 years with the possibility of prolongation.
**Application deadline**:13.03.2024
**Contact**:
Prof. Dr. Holger Sültmann
Phone +49 (0)6221/56-5934
The DKFZ is committed to increase the proportion of women in all areas and positions in which women are underrepresented. Qualified female applicants are therefore particularly encouraged to apply.
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