Nce Dmpk Preclinical Modeling and Simulation

vor 7 Monaten


Darmstadt, Deutschland Merck KGaA Vollzeit

Work Your Magic with us

Ready to explore, break barriers, and discover more? We know you've got big plans '“ so do we Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

**Your role**:
The NCE DMPK preclinical M&S expert is a member of the Discovery Project Team, depending on the phase of the project. As scientific matter expert, you represent the NCE DMPK function ensuring proper flow of information between the project, the function, and key stakeholders. You will also contribute to / lead scientific initiatives designed to improve the M&S capabilities within our drug discovery organization.

**Who you are**:

- Education in either Pharmacokinetics, Pharmaceutical/ Biotechnological Sciences, Biomedical/Chemical Engineering, Applied Mathematics, or a related discipline.
- Master’s degree with 5 years in pharmaceutical/biotechnological industry or Ph.D./Post-Doc preferably with experience in in pharmaceutical/biotechnological industry
- Comprehensive understanding of the concepts of pharmacokinetics and pharmacodynamics during drug discovery & development
- Strong hands-on experience with modeling software (such as: MatLab, R, Phoenix/WinNonlin, NONMEM, Monolix etc).
- Experience with DDI predictions using appropriate static and dynamic approaches is desirable.
- Experience in Python, C/C++ and/or other programming languages would be advantageous.
- Good understanding of related disciplines (pharmacology, toxicology, nonclinical safety, drug design, bioanalytics, etc.) is desirable.
- Fluent spoken and written English, German is a plus.

**What we offer**:We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress


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