Postdoctoral Fellow

vor 1 Woche

Freiburg, Deutschland Universität Freiburg Vollzeit

Bewerbungsfrist: 25.02.2024
- Veröffentlicht: 09.02.2024
- Start-date: At the earliest possible date.
- Fulltime position
- Kennziffer: 00003584

**Beschreibung**:
This position will be filled in the laboratory of Professor **Wolfgang Schamel **with a researcher who has experience in **Molecular Immunology**.

If you are fascinated by the biology of T cells and if you are interested in the mechanisms controlling viral infections or in using new tools to steer immune responses, you are the person we are looking for. Examples of our work can be found in the publications below. We expect that you will work independently with great enthusiasm and integrate into our group and the Excellence Cluster CIBSS. In addition, you will be supervising Master students in the biology program. Knowledge of German is not required. Our group is situated in the new Life Science building of the university (Signalhaus) and we have access to the cell sorting, sequencing, proteomics and imaging facilities.

**To Apply**:
**Selected publications to represent the different topics we work on**:
Herr L, Fiala G, Sagar, int. al, Schamel WW (**2024**) Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals. **Science Advances **in press.

Juraske C, Krissmer S, Teuber E, Parigiani A, int. al, Schamel WW (**2024**) Reprogramming of human γδ T cells by expression of an anti-CD19 TCR fusion construct (εTRuC) to enhance tumor killing. **J Leukoc Biol **115: 293-305

Velasco Cárdenas R, Brandl S, int. al, Schamel WW* & Minguet S* (**2023**) Harnessing CD3 diversity to optimize CAR T cells. **Nature Immunol **24: 2135-2149

Idstein V, Ehret A, Yousefi O & Schamel WW (**2023**) Engineering of an Optogenetic T Cell Receptor Compatible with Fluorescence-Based Readouts. **ACS Synth Biol **12: 2857-2864

Hartl F, Beck-Garcìa E, int. al, Schamel WW* & Minguet S* (**2020**) Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function. **Nature Immunol **21: 902-9133
- shared last authorship

The position is initially limited to two years.

**Bewerbung**:
University of Freiburg
CIBSS
Prof. Dr. Wolfgang Schamel/
Angelika Reichinger
Schänzlestraße 18
79104 Freiburg

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