2 Postdoc Positions for Electrical and Optical

vor 7 Monaten


Freiburg, Deutschland Universitätsklinikum Freiburg Vollzeit

The Institute of Physiology of the University of Freiburg has two openings in Biophysics**2 Postdoc Positions for Electrical and Optical Analysis of Nanopores for Protein Sequencing Using Single-Molecule Tools (M/F/d)**:

- Biological and solid state nanopores play an increasing role in molecular diagnostics. The goal of this project is to establish their use for the identification of peptides and their post-translational modifications that are found in a variety of pathological conditions, including cancer, cardiovascular, neurodegenerative, and infectious diseases. Simultaneous observation of the electrical current through a single nanopore, and the optical signal from a dye molecule inside the pore will provide characteristic information of the peptide bound in the pore.- **The responsibilities of the successful applicants (M/F/d) will include**:

- Design and construction of a combined electrophysiology/microscopy setup
- Wet lab work for fabrication of nanopores in lipid bilayers
- Molecular biology and biochemistry to generate chimeric and mutant pore proteins
- Experiments and data analysis
- Comprehensive presentation of results in group meetings and at conferences
- Preparation of manuscripts

**What we are looking for**:

- Strong interest in microscopy, electrophysiology, instrument design and nanopore physics
- Experience in electrophysiology and/or microscopy
- Background in programming, molecular biology, and biochemistry
- Ability to work independently and in a team

**Applications should include**:

- Curriculum vitae with your name, address, degree(s) with transcript(s) of grades, research experience, educational and employment history; please include any awards, distinctions and publications
- Motivation letter
- The preferred starting date is as soon as possible. The positions are initially limited for two years with a renewal option.**Questions? Please contact**:

- Prof. Jan Behrends, Institute of Physiology Dr. Maximilian Ulbrich, BIOSS Centre for Biological Signalling Studies- Allgemeiner Hinweis: Die Vergütung erfolgt nach Tarif. Vollzeitstellen sind grundsätzlich teilbar, soweit dienstliche oder rechtliche Gründe nicht entgegenstehen. Schwerbehinderte werden bei gleicher Eignung besonders berücksichtigt. Einstellungen erfolgen durch die Abteilung Personalbetreuung.


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