Research Scientist/Senior Research Scientist

vor 2 Wochen


Munich, Deutschland mbiomics GmbH Vollzeit

Research Scientist/Senior Research Scientist – Immunology/Host Screening

Company Summary:


mbiomics was founded in 2020 by an experienced management team with a vision to deliver effective microbiome-based therapeutics that will change the treatment paradigm for many chronic diseases. We have recently closed a Series A round, enabling us to revolutionize the development of breakthrough live-bacterial therapeutics (LBT). mbiomics is leveraging innovative screening and manufacturing technologies as well as its tailored microbiome analysis platform to overcome challenges in complex LBT development – by providing precision profiling data for improved bacterial consortia selection, patient stratification, and patient monitoring for clinical trials.


Position Summary: 


This position in the mbiomics’ R&D team will drive key aspects of mbiomics’ therapeutic and diagnostic development goals. The Scientist/Senior Scientist will be tasked with developing a screening platform with a focus on microbiota-host interactions and will proactively and independently identify and operationalize opportunities for innovation and platform de-risking across the organization. The Scientist/Senior Scientist will have expertise in the microbiome and its interaction with the host in health and disease, will provide project and team leadership and will be an excellent collaborator and communicator both with internal and external stakeholders.  


Responsibilities/Duties


  • Propose biological hypotheses for mechanisms underlying the efficacy of microbial interventions and develop a screening platform for host-microbe interactions for product relevant mechanisms of action
  • Design, develop and execute in vitro, ex vivo, and in vivo assays to assess host-microbial interactions and immunological effects mediated by mbiomic’s products
  • Work closely with mbiomics’s data scientists to translate in silico hypotheses and translationally de-risk screening results with large clinical datasets
  • Support translational development of host biomarkers for microbial interventions in clinical studies
  • Perform regular risk and feasibility assessments to inform modifications to workstreams and project timelines
  • Build and manage an effective team of Research Associates and Research Scientists to execute workstreams, including collaboratively defining clear work plans, coordinating resource availability for experiments, ensuring good documentation practices, and responding to feedback from the team
  • Work effectively across different multifunctional teams and projects in the design and development of microbial therapeutics
  • Effectively communicate development plans, experimental outcomes, and project updates to a variety of audiences including associates, scientists, leadership and external stakeholders such as research and clinical collaborators


Required Skills and Competencies:


  • Proven expertise in microbiome therapy development
  • Ability to apply best practice in therapeutic development and resource-constrained decision making to make judgements about workstream risk, R&D strategy, and team dynamics
  • Proven expertise in designing and developing in vitro screening assays for host-microbial interactions ranging from small to high throughput
  • Expertise in microbiome in vivo assay development including gnotobiotic mouse colonization and disease models
  • Strong organizational and communications skills as required for organizing and leading projects or multifunctional teams
  • Eagerness to work collaboratively in a team and to both give and receive feedback to teammates.
  • Ability to prioritize a variety of objectives
  • Passion and excitement to drive research and development forward
  • Desire to pursue professional development by acquiring new skills, presenting work at internal and external venues, and acting on feedback
  • Attract new talent to the team by building and leveraging professional network


Education and Experience


  • PhD in Microbiology, Immunology, Cell Biology or a related field
  • Minimum 3 years post-PhD experience in one or more the following areas: microbiome, drug development, screening assay development, biomarker discovery and development
  • 2-5 years of experience in a microbiome therapeutics development environment in academia or industry
  • Minimum of 2 years of experience as a team or a project lead managing RA or RS level team members in an industry setting





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