Fully Funded PhD position in cardiac electrophysiology

vor 2 Monaten


Freiburg, Deutschland Universitätsklinikum Freiburg Vollzeit
The Dept. University Heart Center Freiburg-Bad Krozingen is a highly specialised center for heart, cardiovascular and circulatory diseases and enjoys an international reputation. With 1500 staff, the heart centre is one of the largest of its kind in Europe. The vision for its translational research centre, the Institute for Experimental Cardiovascular Medicine (IEKM), is to build bridges between basic and clinical research and to drive the advancement of knowledge on cardiovascular disease and therapy.

Fully Funded PhD position in cardiac electrophysiology (m/f/d)

The Institute of Experimental Cardiovascular Medicine (IEKM) is a modern, internationally organised research institute with flat hierarchies and currently around 40 employees and students.

Atrial fibrillation (AF) is a highly prevalent cardiac arrhythmia, affecting 59 million people globally. Current medications are largely ineffective in stopping AF. This project seeks to develop and validate a novel model for studying AF and to identify new drugs with the potential to successfully halt the arrhythmia.

We Offer

  • an outstanding international and interdisciplinary scientific environment with English as the working language
  • access to up-to-date laboratories, cutting-edge technologies and state-of-the-art infrastructure
  • highly personalised supervision at the forefront of integrative biomedical sciences
  • a diverse, vibrant and multi-cultural environment with the beautiful Freiburg located at the crossroads of Germany, France, and Switzerland
  • membership of the Spemann Graduate School of Biology and Medicine (SGBM), offering additional networking opportunities, translational skills training, and career guidance

Research Will Cover

  • optimisation of an atrial slice model for acute electrophysiological and mechanical measurements as a novel platform to study atrial tissues and AF
  • validation of the model by assessing the preservation of key physiological responses and effects of well-known drugs altering action potential duration
  • test of a selection of novel pharmacological compounds in collaboration with Novartis to fight AF Main techniques involved: live tissue slices, the sharp electrode technique and 3D imaging

Qualifications And Requirements

  • self-motivated students who hold an excellent (top 10%) MSc or equivalent in Biology or in disciplines relevant to biomedical research such as Biophysics and Physiology
  • research experience in cell/ tissue culture and in electrophysiology is strongly recommended
  • a solid background in electrophysiology is highly desired
  • scientific curiosity and the desire to actively shape your own research project are a must
  • excellent communication skills in English (B2 or higher)

The Mechanobiology Section of the IEKM offers a 3-year PhD position.

Are you interested? Then we look forward to receiving your online application with all relevant documentation.

Contact For More Details About The Position

remi.peyronnet@uniklinik-freiburg.de

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