Research Fellow

vor 2 Wochen


Ludwigshafen am Rhein, Deutschland AbbVie Deutschland GmbH & Co. KG Vollzeit

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn . Principal Research Scientist I (all genders) Medicinal Chemistry (permanent / full-time)
The job that makes possibilities real in patients' lives. Welcome to AbbVie As part of an international company with 48,000 employees worldwide and around 3,000 employees in Germany, you will have the opportunity of addressing some of tomorrows unmet medical needs in close collaboration with your colleagues. Are you passionate about improving global health care? In a challenging work environment that offers opportunities of developing and increasing your own skills? Small Molecular Therapeutics and Platform Technologies (SMTPT) within Discovery Research in Ludwigshafen (Germany) seeks an accomplished scientist to lead a team of medicinal chemists within the Global Medicinal Chemistry (GMEC) organization. The Principal Research Scientist will lead a team of chemists designing and synthesizing small molecules aimed at identifying and advancing promising low dose leads.
They will be responsible for managing a diverse team of scientists who design and synthesize drug candidates for novel targets throughout AbbVie's drug discovery pipeline, and may serve as Medicinal Chemistry Lead for some of these efforts. She / He / They will have a strong background in synthetic chemistry who has demonstrated high productivity in synthesizing complex organic molecules. She / He / They and team will develop novel medicinal chemistry strategies and execute multiparametric optimization(s) of drug candidate properties in a highly collaborative environment aimed at accelerating the delivery of a sustainable pipeline of first in class / breakthrough small molecule drug candidates with transformative potential.
The candidate will have experience with strategic planning, and leadership of medicinal chemistry teams, as well as working with cross-functional teams. The candidate will have a strong expertise in modern medicinal chemistry, including an appreciation of modern computational and experimental tools, multidisciplinary inputs, and synthetic technologies needed to develop low dose small molecule drug candidates. Strong communication skills are essential, as the candidate must be able to tailor interactions with technical teams and represent the medicinal chemistry advances to AbbVie leadership.
In your role, you will lead international Medicinal Chemistry teams and partner cross-functionally to advance projects by applying state-of-the-art methodologies in drug discovery
You will lead internal Medicinal Chemistry teams and/or steer teams at our CRO partners in the design and synthesis of low dose drug candidates and the development of stage-appropriate progression funnels for their identification from research to development
As programs advance, work with key stakeholders in the Development sciences core team to address and reduce risks in collaboration to drive towards candidate nomination
Lead chemistry team activities and maintain a high level of productivity in the laboratory setting
Promote professional development of a team of scientists through effective mentoring, guidance, and supervision
Present program updates and research strategies to functional and non-functional leaders as well as potential and existing partners
Maintain awareness of emerging literature and science in the field and author scientific disclosures / publications
Maintain scientific presence outside AbbVie with appropriate publication and conference abstract submission highlighting innovative medicinal chemistry learnings
A mix of on-site and remote working will be possible in alignment with the role responsibilities
PhD with typically 6+ years of experience in organic or medicinal chemistry or equivalent field with 6+ years of relevant work experience in biotech or pharma. BS or equivalent education and extensive, Typically, 14+ years of experience; MS or equivalent education with typically 12+ years of experience
Extensive knowledge and experience in modern medicinal chemistry, preferably also in the field of protein degradation and CNS-drug development
Highly organized and self-directed, experience leading medicinal chemistry teams
Proven track record of productivity in the laboratory setting
Excellent written and verbal communication is required, as well as critical evaluation and data-driven decision-making
Proven chemistry team leadership and management abilities, including experience mentoring, guiding, supervising, and developing early career chemists
with a diverse work environment where you can have a real impact
with an attractive salary
with an intensive onboarding process with a mentor at your side
with flexible work models for a healthy work-life balance
with a corporate health management that offers comprehensive health and exercise programs
with company social benefits
with a wide range of career opportunities in an international organization
with top-tier, attractive development opportunities
with a strong international network
Multiple times, we have been globally recognized as a "Great Place to Work" and we are proud to provide our employees with the flexibility to maintain a healthy work-life balance. Sounds like the perfect career opportunity for you? 999Z FULL_TIME



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