PhD Student in Quantitative Spatial Cancer biology research group
vor 6 Monaten
"Knowledge becomes health" - we are filling this motto with life every day, developing new ideas and improv-ing old-established knowledge. The University Hospital Frankfurt has existed since 4. Our around 7, employees contribute with their skills and knowledge to the specialist clinics, theoretical clinical institutes, and administrative departments. The close connection of health care with research and teaching, as well as a climate of collegiality, internationality, and cross-professional cooperation characterize the university hospital.
PhD Student in Quantitative Spatial Cancer biology research group
(We are targeting applicants of all genders)
Full time | limited up to 4 years | Announcement number: -4
We are seeking a motivated PhD Student to join our „ Quantitative Spatial Cancer Biology" research group at the Dr. Senckenberg Institute of Pathology MSNZ Frankfurt , an excellence program supporting careers in Translational Cancer Research (funded by the German Cancer Aid).
The lab, headed by Dr. Konstantinos Kokkaliaris, specializes in hematopoietic stem-cell biology and bone marrow tissue organization in health and cancer. We use innovate single-cell protein profiling technologies including cutting-edge multiplexed tissue imaging, multicolor flow cytometry and mass cytometry. The focus of the lab is to better understand tissue organization in homeostasis, cancer and aging and further develop multiplex tissue imaging modalities.
Publications:
Kokkaliaris KD**, et al, Adult blood stem cell localization reflects the abundance of reported bone marrow niche cell types and their combinations. Blood. 0; ():6-7. *co-corresponig author, Cover story
Coutu DL'. Kokkaliaris KD*. Kunz L* and Schroeder T. Multicolor quantitative confocal imaging cytometry. Nature Methods 8; :- *co-first authors
Coutu DL*. Kokkaliaris KD*. Kunz L and Schroeder T Three-dimensional map of non-hematopoietic bone marrow cells and molecules. Nature Biotechnology 7, () 2-0. - co-first authors, Cover Story
Your role
Clonal hematopoiesis (CH) is a common age-related condition characterized by the outgrowth of mutated hematopoietic clones which can lead to life-threatening malignancies. CH is caused by mutations in hematopoietic stem cells (HSCs) and is accelerated in individuals with ischemic hearth failure. This DFG funded project aims to define the key bone marrow components and cell-extrinsic signais involved in promoting CH following hearth failure. Using established animals models, patient cohorts and cutting-edge single-cell quantitative biology, we will uncover the underlying mechanism of targeted candidate signals from bonw marrow niches. Our goal is to leverage those findings towarsds the design of novel therapeutic strategies to decelerate outgrowth of mutated hematopoietic clones.
Who you are
Master’s degree in Life Sciences or equivalent Basic experience in laboratory techniques (i.e. molecular biology) Background in immunofluorescence microscopy and hematopoiesis are a plus Passion for discovery, collaborative spirit & good communication skills Good knowledge of spoken and written English Due to legal regulation, a valid proof of measles immunity / measles vaccination is required.
What we offer
Collective agreement : In addition to an attractive salary based on a collective agreement (% E) with an annual special payment, you benefit from long-term security through company pension schemes Mobility : Free public transport in all Hessen (Free State Ticket Hessen) Campus : Our attractive university hospital campus offers a modern cafeteria, various cafes, and opportunities to rest in numerous green spaces. A walk on the riverside of the Main offers relaxation during breaks Work-Life-Balance : Part-time employment is possible, we offer childcare in our daycare center (if you have any questions, please contact Ms. Häfner at / 1 ), child care during holidays Health Promotion: Benefit from our attractive health offers. We offer regular online and face-to-face courses on nutrition, relaxation, sports and excercies. Professional development : Internal and external training for your professional developmentWomen are underrepresented in these positions at the University Hospital Frankfurt. Applications from women are therefore particularly welcome. Disabled applicants are preferred if they have the same personal and professional qualifications.
Join our team
-
PhD Researcher in Lymphoma Cancer Biology
vor 3 Wochen
Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitResearch Opportunities at Universitätsklinikum Frankfurt">We are seeking a highly motivated PhD student to join our team at the Universitätsklinikum Frankfurt. Our research focuses on understanding the molecular mechanisms underlying aggressive lymphomas.About the ProjectThe project aims to investigate oncogenic signaling pathways in lymphoma models using...
-
PhD Student Position in Lymphoma Research
vor 6 Monaten
Frankfurt, Deutschland Universitätsklinikum Frankfurt Vollzeit"Knowledge becomes health" - we are filling this motto with life every day, developing new ideas and improv-ing old-established knowledge. The University Hospital Frankfurt has existed since 4. Our around 7, employees contribute with their skills and knowledge to the specialist clinics, theoretical clinical institutes, and administrative departments. The...
-
PhD student position Part-time
Vor 6 Tagen
Frankfurt am Main, Deutschland Universitätsklinikum Frankfurt VollzeitNaturwissenschaften Hessen Teilzeit Naturwissenschaft und Forschung Fachkraft Forschung, Lehre, Entwicklung The key goal of the research project is to develop novel drugs and degrader molecules to target survival pathways in aggressive lymphomas (DLBCL). The project is based on our previous work discovering new drug target candidates that are highly...
-
Post - Doctoral Researcher
vor 5 Monaten
Frankfurt, Deutschland Universitätsklinikum Frankfurt Vollzeit"Knowledge becomes health" - we are filling this motto with life every day, developing new ideas and improv-ing old-established knowledge. The University Hospital Frankfurt has existed since 4. Our around 7, employees contribute with their skills and knowledge to the specialist clinics, theoretical clinical institutes, and administrative departments. The...
-
PhD Student
vor 6 Monaten
Frankfurt, Deutschland Universitätsklinikum Frankfurt Vollzeit„Aus Wissen wird Gesundheit“ – wir füllen dieses Motto tagtäglich mit Leben, entwickeln neue Ideen und Altbewährtes weiter. Das Universitätsklinikum Frankfurt besteht seit 4 und unsere rund 7. Beschäftigten bringen sich mit ihrem Können und Wissen an den Fachkliniken, klinisch theoretischen Instituten und in den Verwaltungsbereichen ein. Die...
-
PhD Position in Virology Research
Vor 5 Tagen
Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitThe Universitätsklinikum Frankfurt is a renowned institution with a rich history dating back to 1914. Our team of approximately 8,500 employees strives for excellence in healthcare, research, and teaching.Job OverviewWe are seeking a highly motivated PhD student to join our interdisciplinary research team at the Institute of Medical Virology. The successful...
-
Radiation Biologist in Space Research
vor 3 Wochen
Frankfurt am Main, Hessen, Deutschland GSI Helmholtzzentrum für Schwerionenforschung VollzeitJob DescriptionGSI Helmholtzzentrum für Schwerionenforschung, a leading institution in particle accelerator science, invites applications for a Radiation Biologist in Space Research. Company OverviewThe new FAIR facility, one of the world's largest research projects, is being built at GSI and FAIR. This international environment offers the opportunity to...
-
PhD Researcher in Translational Neuroscience
Vor 5 Tagen
Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt Vollzeit**About Us**The Universitätsklinikum Frankfurt is a leading academic hospital with a rich history dating back to 1914. Our hospital has approximately 8,500 employees who contribute their skills and knowledge to various specialist clinics, theoretical clinical institutes, and administrative departments.Our unique environment combines healthcare, research,...
-
Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitJob OverviewWe are seeking a highly motivated and experienced Senior Bioinformatics Research Scientist to join our team at the University Hospital Frankfurt. The successful candidate will be responsible for conducting advanced bioinformatics analyses and developing new computational tools to investigate the crosstalk between the microbiome and disease...
-
PhD Researcher in Drug Development and Discovery
Vor 6 Tagen
Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitAbout Universitätsklinikum FrankfurtUniversitätsklinikum Frankfurt is a renowned research institution at the forefront of medical innovation. Our team of experts is dedicated to pushing the boundaries of knowledge in various fields, including cancer research and drug development.
-
Quantitative Research
vor 7 Monaten
Frankfurt am Main, Deutschland JPMorgan Chase & Co Vollzeit**JOB DESCRIPTION** This is an opportunity to work on challenging quantitative topics in a highly international environment in close collaboration with our Quantitative Research (QR) partners in in London, New York, Mumbai and Paris. As a Quantitative Research - Counterparty Credit Risk Associate within the Risk Management team you will be a part of the...
-
(Global) Ai Research Intern
vor 6 Monaten
Frankfurt am Main, Deutschland Lunit Vollzeit**Conquering cancer through AI"**: Lunit, a portmanteau of ‘Learning unit,’ is a medical AI software company devoted to providing AI-powered total cancer care. Our AI solutions help discover cancer and predict cancer treatment outcomes, achieving timely and individually tailored cancer treatment. **️ About the team** - You will work in the AI...
-
Quantitative Research Associate
vor 4 Wochen
Frankfurt am Main, Hessen, Deutschland DE014 NERA Economic Consulting Gmbh VollzeitAbout NERA Economic ConsultingNERA Economic Consulting GmbH is a leading global firm of experts dedicated to applying economic, financial, and quantitative principles to complex business challenges.We bring academic rigor, objectivity, and real-world industry experience to bear on issues arising from competition, regulation, public policy, strategy, finance,...
-
PhD Researcher in Neuropsychobiology of Aggression
vor 2 Wochen
Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitThe Universitätsklinikum Frankfurt offers a part-time PhD position (65%) for a limited period of 3 years within the Transregional Collaborative Research Center TRR 379 Neuropsychobiology of Aggression. Our research team focuses on elucidating the pathophysiological, genetic, and molecular mechanisms of mental disorders, aiming to identify novel tailored...
-
PhD Researcher in Translational Psychiatry
vor 2 Wochen
Frankfurt am Main, Hessen, Deutschland Universitätsklinikum Frankfurt VollzeitAbout UsThe Universitätsklinikum Frankfurt is a leading research hospital with a rich history dating back to 1914. With over 8,500 employees, our institution excels in the fields of health care, research, and teaching.Our MissionWe strive to provide top-notch medical care while pushing the boundaries of scientific knowledge. Our interdisciplinary approach...
-
Phd Traineeship in Macroprudential Policy and
vor 3 Monaten
Frankfurt am Main, Deutschland The European Central Bank Vollzeit**General Information*** **Type of contract** PhD traineeship **Who can apply?** EU nationals eligible for our traineeship programme **Grant** The trainee grant is €2,120 per month plus an accommodation allowance (see further information section) **Working time** Full time **Place of work** Frankfurt am Main, Germany **Closing date**...
-
One Phd Student
vor 2 Monaten
Frankfurt am Main, Deutschland Max-Planck-Institut für Rechtsgeschichte und Rechtstheorie VollzeitThe in Frankfurt/Main is a world leader in fundamental research on law. Its three research departments with more than 70 scholars, the unrivalled collections of its specialized library, and its numerous national and international co-operations make it the central research hub for a global scientific community investigating the past, present and future of...
-
Intern, Quantitative Research
Vor 5 Tagen
Frankfurt am Main, Deutschland Invesco VollzeitAs one of the world’s leading asset managers, Invesco is dedicated to helping investors worldwide achieve their financial objectives. By delivering the combined power of our distinctive investment management capabilities, we provide a wide range of investment strategies and vehicles to our clients around the world. If you're looking for challenging work,...
-
Research Assistant/doctoral Student
vor 6 Monaten
Frankfurt am Main, Deutschland Leibniz-Institut für Finanzmarktforschung SAFE VollzeitThe Leibniz Institute for Financial Research SAFE is seeking to fill the position of a Research Assistant/Doctoral Student (f/m/d) in the area of Law & Finance, Proj. SaiLEur Timeframe 70% Position Fixed-Term fixed term for 3 years Payment salary group E13 TV-H Start at the earliest possible date The Leibniz Institute for Financial Research SAFE -...
-
Phd Position
vor 6 Monaten
Frankfurt am Main, Deutschland Senckenberg VollzeitThe Senckenberg Gesellschaft für Naturforschung (SGN) was founded in 1817 and is one of the most important research institutions in the field of biodiversity. At its eleven locations throughout Germany, scientists from over 40 nations conduct cutting-edge research at an international level. At the Senckenberg Research Institute and Natural History Museum...
