Master Thesis: Development of Synthetic Lymph Nodes to study Leukemia Therapy Resistance
Vor 2 Tagen
INM's research group Immuno-Materials combines expertise from synthetic biology, biomaterials and immunology to develop new approaches for studying and regulating immune reactions.Are you a master student (f/m/d) with a background in cell biology, biomaterials or biophysics (or related fields) and looking for a thesis project? This might be something for youMaster Thesis:Development of synthetic lymph nodes to study leukemia therapy resistanceStarting on February 1st, 2026 (with flexibility).We have pioneered the development of synthetic lymph nodes formed from artificial cells that can mimics the microenvironment of leukemia cells. This approach can be applied to form artificial tumor microenvironments with defined properties and systematically study therapy resistance mechanisms. We are able to induce specific molecular and biophysical changes in the synthetic lymph nodes that mimic the signaling induced by the extracellular matrix and other immune cells in the lymph nodes. The master thesis should study the effects of the extracellular matrix in conjunction with intercellular signaling on therapy resistance of chronic lymphocytic leukemia.Techniques applied include:3D cancer cell cultureImmuno-staining with flow cytometry analysisAdvanced microscopy (light-sheet microscopy, confocal fluorescence microscopy)Biochemical and radiometric assaysInterested?We are looking forward to receiving your application (CV, B.Sc. certificate or transcripts of record, motivation letter) by December 15th, 2025. Please send it via our online applications system (single pdf file < 5 MB).The INM practices an open and appreciative corporate culture in which the existing diversity is promoted and lived. The institute is an equal opportunity employer with a certified family-friendly policy, and it provides offers for a better work-life balance, flextime, and mobile working. We promote professional opportunities for women and strongly encourage them to apply. Severely disabled applicants with equal qualifications and aptitude will be given preferential consideration.
-
Saarbrücken, Saarland, Deutschland INM - Leibniz-Institut für Neue Materialien gGmbH Vollzeit 38.000 € - 45.000 € pro JahrThe Innovative Electron Microscopy Department develops and applies electron microscopy methodologies for nanoscale and atomic-resolution characterization of soft functional materials and their interfaces, with specific focus on soft-hard interfaces.PhD STUDENT (F/M/D): electron microscopy of soft functional materialsWe are looking for a highly motivated PhD...
-
Cluster Director of Sales
vor 1 Woche
Saarbrücken, Saarland, Deutschland HRG Hotels Vollzeit 80.000 € - 120.000 € pro JahrDie HR Group ist eine der am schnellsten wachsenden Hotelbetreibergesellschaften im deutschsprachigen Raum. Zu unserem Portfolio gehören derzeit über 190 Hotels in der Nähe von Messen und Flughäfen, sowie zentral gelegene Stadthotels und Hotels & Resorts in beliebten Ferienregionen.Unser Hauptgeschäftsfeld besteht im Erwerb und Betrieb von...
-
Werkstudent:in Salesforce Development
vor 2 Wochen
Saarbrücken, Saarland, Deutschland Peak & Peak GmbH Vollzeit 30.000 € - 50.000 € pro JahrWir suchen dich als Unterstützung für unser Development-Team Wenn du Lust hast, Praxisluft in der Softwareentwicklung zu schnuppern und deine Skills weiter auszubauen, bist du bei uns genau richtig.Bitte beachte, dass du für diese Stelle in Deutschland sein musst, eine gültige Immatrikulationsbescheinigung benötigst und noch mindestens 2 Semester...
-
DevOps Engineer
vor 9 Stunden
Saarbrücken, Saarland, Deutschland Chapter 2 VollzeitARIS, the Process Intelligence leader and part of Software GmbH, helps organizations turn their processes into value. By managing the entire process lifecycle with a single, integrated suite, ARIS enables companies to define, analyze, simulate, optimize and control their processes.ARIS is consistently recognized by Gartner and Forrester as a leader in...
-
Senior QA Engineer
vor 1 Stunde
Saarbrücken, Saarland, Deutschland Xempus Deutschland GmbH VollzeitWho we areWe are Xempus, Germany´s leading independent Software-as-Service (SaaS) platform for the management and distribution of pension, life and health insurance. Our mission: making pension, life and health insurance digital and understandable, efficient and accessible for everyone. Since 2007, we have been constantly working to drive the digitalization...
-
Software Developer Frontend
vor 7 Stunden
Saarbrücken, Saarland, Deutschland Athereon GRC GmbH VollzeitYour missionYour Tasks:You develop features and improvements for our frontend single-page application in React (JavaScript / TypeScript).As an experienced software developer, you coordinate with your colleagues in the frontend team and all relevant stakeholders (product management, backend development, UX, sales, etc.).You support the technical documentation...
-
Web Developer
Vor 6 Tagen
Saarbrücken, Saarland, Deutschland BASIS Europe Vollzeit 60.000 € - 120.000 € pro JahrYour missionYou will...Work with other engineers to help architect, build and scale our set of web components and BBj PluginsDesign and implement new features, enhancements, and optimizationsParticipate in technical discussions, research, and develop new innovative ways to improve our productContribute to knowledge tools, communities, and...
-
Application Engineer
vor 1 Woche
Saarbrücken, Saarland, Deutschland Stahl- und Apparatebau Hans Leffer GmbH & Co. KG Vollzeit 40.000 € - 80.000 € pro JahrLassen Sie uns gemeinsam die Zukunft gestaltenApplication Engineer - Foundation Engineering (all genders)with readiness to travel internationallyWe are Stahl- und Apparatebau Hans Leffer GmbH & Co. KG - a family-run company, founded in 1946, with a long tradition and a great spirit of innovation. As a company, LEFFER represents quality, reliability and...
-
Service Engineer
vor 2 Wochen
Saarbrücken, Saarland, Deutschland Stahl- und Apparatebau Hans Leffer GmbH & Co. KG Vollzeit 45.000 € - 75.000 € pro JahrLassen Sie uns gemeinsam die Zukunft gestaltenService Engineer - Foundation Engineering (all genders)with readiness to travel internationallyWe are Stahl- und Apparatebau Hans Leffer GmbH & Co. KG - a family-run company, founded in 1946, with a long tradition and a great spirit of innovation. As a company, LEFFER represents quality, reliability and...
-
Medical Science Liaison
Vor 6 Tagen
Saarbrücken, Saarland, Deutschland Nordberg Medical Vollzeit 60.000 € - 150.000 € pro JahrTake part in a journey committed to innovation and improving livesNordberg Medical is a Swedish biotech company working at the forefront of biomaterial science to reverse functionality loss. With state-of-the-art biomaterials, we produce and market innovative medical products that target structural imbalances associated with aging.In 2021, we passed a...
