PhD Student

wanted for 01. February 2026 at departement of Gastroenterology and Hepatology.

We invite applications from highly motivated PhD candidates to join our distinguished research team undertaking an advanced project on the role of gut microbiota in mediating resistance to immunotherapy and chemotherapy in colorectal cancer. The project will be conducted within a close collaboration between University Hospital Heidelberg and DKFZ. The successful candidate will contribute to a multidisciplinary collaboration focused on identifying microbial-derived factors that influence tumor immunogenicity. The project aims to uncover and validate novel therapeutic targets and combination strategies to overcome microbiome-associated immune suppression in colorectal cancer.

Job-ID:

V

Field of application:

Klinik für Gastroenterologie, Infektionen und Vergiftungen

Location:

Heidelberg

Job Category:

Science and teaching

Working hours:

Part time (65 %)

Published:

Limitation:

Temporary (4 years)

Contract:

TV-L

• Participate in recruitment and biobanking of patient material
• Integrate comprehensive multi-omics datasets—including metabolomics, high-dimensional flow cytometry, and multiplex imaging—to accurately determine crucial molecular and cellular processes in colorectal cancer
• Carry out experimental validation using both in vitro models derived from mouse and human organoids and in vivo studies using advanced preclinical systems to confirm mechanisms and the effectiveness of identified drug candidates

• Hold a Master's degree or an equivalent qualification in a relevant discipline such as Cancer Biology, Immunology, Microbiology, or related fields.
• Meet all academic requirements specified by the Heidelberg Biosciences International Graduate School (HBIGS)
• Possess strong expertise in molecular and cellular biology methods, including high-dimensional flow cytometry, gene expression profiling, and both two-dimensional and three-dimensional cell culture, alongside microbiology techniques.
• Experience with metabolomics and proficiency in data analysis are highly preferred.
• Exhibit excellent communication and organizational abilities, capable of working independently as well as in collaborative team environments.

• Goal-oriented, individual training and development opportunities (e.g. courses for flow cytometry)
• Working with the latest techniques / technical equipment
• Possibility of doctorate
• Possibility to publish scientifically is offered and supported
• Regular team meetings
• Interdisciplinary cooperation with DKFZ Heidelberg
• Collectively agreed remuneration (TV-L E13), attractive company pension scheme (VBL)
• 30 days vacation
• Sustainable travel: job ticket
• Family-friendly working environment: cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of care
• Wide range of health, prevention and sports offers

For further information please contact Dr. Conrad Rauber via

Interested?

Applications will be accepted until via online.

Klinik für Gastroenterologie, Infektionen und Vergiftungen

Dr. Conrad Rauber

Im Neuenheimer Feld 410

69120 Heidelberg

Note: The UKHD is subject to the provisions of the Infektionsschutzgesetz. Therefore, a valid measles immunity certificate is required for all persons employed at the UKHD.

The UKHD embraces diversity and values diversity.

Regardless of age, gender, sexual identity, disability, origin or religion, we offer everyone the same opportunities. If one gender is underrepresented in a particular area, we place particular emphasis on counteracting this imbalance. If they have the same aptitude, qualifications and professional performance, we give priority to people with severe disabilities when considering them for vacancies.

Classification is based on qualifications and personal requirements. The salary (gross) is for a full-time position and does not include the annual bonus or other allowances.