Doctoral Student
vor 19 Stunden
For the
field of Translational Anaesthesiology and Intensive Care
, we are looking for a Doctoral Student (m/f/d) for enhancer-driven viral tools for neuronal subtypes, starting as soon as possible. The position is limited to 2 years with the possibility of extension and requires a commitment of 25 hours per week.
We are seeking a highly motivated PhD student to join a multidisciplinary research project focused on developing viral-based tools for specific labelling and functional manipulation of transcriptionally defined neuronal subtypes.
The project integrates RNA sequencing analysis with state-of-the-art approaches in neuronal manipulation, including PSAMs and DREADDs, to identify and validate enhancer-driven viral constructs for selective labelling and manipulation of neuronal subtypes.
The research program is structured into three main objectives:
- Bioinformatics analysis to identify subtype-specific enhancers.
- Experimental validation of candidate enhancers.
- Development and testing of enhancer-driven viral constructs for neuronal manipulation.
Your Activities and Responsibilities
- Conduct bioinformatic analyses using enhancer databases and deep learning tools to establish selection criteria for enhancers
- Establish and optimize primary neuronal cell cultures
- Perform viral production and carry out quality control assays
- Contribute to data analysis, interpretation, figure preparation, and manuscript writing
- Collaborate with internal and external partners and actively participate in lab meetings, training sessions, and conferences
Your Qualifications
- Master's degree (or equivalent) in Neuroscience, Biology, Bioinformatics, or a related discipline
- Proven experience in programming/coding (Python, Matlab, or R) and willingness to learn new approaches
- Hands-on experience with primary neuronal cell culture
- Familiarity with viral tools (e.g., AAVs)
- High level of motivation, reliability, and independence, combined with the ability to work effectively in a team
- Strong written and verbal communication skills in English
What we offer
- The grouping takes place in TV-L taking into account your qualifications and personal requirements including the social benefits customary in the public service (company pension, annual special payment)
- Access to cutting-edge technologies and a collaborative research environment
- Integration into an internationally oriented research group
- Support for presenting your work at national and international conferences
- Employee benefits in various companies
Contact
Dr. Oumayma Aousji
Translational Anesthesiology
0821/
Application Process
Please upload your documents by the
We look forward to your application
In addition to exciting tasks in a variety of fields, the university hospital offers you numerous attractive benefits and a meaningful job. You can find more information hier.
The position is suitable for people with severe disabilities. Applicants (m/f/d) with severe disabilities will be preferred if they are essentially the same aptitude, ability and professional performance. Women are invited to apply in accordance with Article 7 (3) BayGlG. When starting work at the Augsburg University Hospital, proof of sufficient immune protection in accordance with
- 23, 23a IfSG must be presented or the same must be met.
