PhD student

Vor 5 Tagen

Göttingen, Deutschland Universitätsmedizin Göttingen UMG Vollzeit 8.300 € - 9.500 € pro Jahr

Ihre Aufgaben

The PhD candidate at the UMG will work closely with the interdisciplinary SMACHONDRON partners to analyze a biobank of primary chondrocytes from SMA patients and to characterize corresponding bone and cartilage samples using high-resolution µCT, synchrotron imaging, and histology. The candidate will assess cell viability, growth, and differentiation profiles of patient-derived chondrocytes, and integrate these findings with 3D structural analyses of patient and mouse bone tissue. All imaging-based results will be validated through standardized histological and immunohistochemical methods.

Ihre Qualifikationen

Successful candidates with a master in Medical Informatics, Engineering, Life Science, or related subjects have a keen interest and strong background in imaging technologies, biology and data analysis. Experience in µCT imaging strategies, multi-modal data registration, 3D image processing as well as in cell culture and histological methods would be of advantage. A certified course to handle laboratory animals would be an asset. The applicant should furthermore enjoy cross-disciplinary work in physics, biology, genetics and medicine. A good command of English is a requirement.

Wir bieten

  • Competitive research in an inspiring, international and world-class environment
  • Broaden your skill set by learning to apply cutting-edge technologies such as synchrotron phase contrast CT and handle patient-derived material, carry out cell isolation, and perform molecular characterization of SMA samples.
  • Further training and career development opportunities; free in-house language courses
  • A wide range of offers to help you balance work and family etc.

Einleitungstext

Members of the interdisciplinary project SMACHONDRON — PD Dr. Kai Böker (Department of Trauma Surgery, Orthopedics, and Plastic Surgery), Prof. Dr. Christian Dullin (Department of Cardiac Imaging), and Prof. Dr. Anna Hell, Head of the Pediatric Orthopedics Division at the Department of Trauma Surgery, Orthopedics, and Plastic Surgery at the University Medical Center Göttingen (UMG) — which investigates developmental, molecular, and clinically relevant alterations in bone and cartilage in spinal muscular atrophy (SMA) and aims to translate innovative therapeutic strategies into clinical practice, invite applications for a position as

PhD Fellow (f/m/d) for 3 years – multi-modal characterization of bone-cartilage interfaces

Within the collaborative project SMACHONDRON between the University Medical Center Göttingen (UMG) and Hannover Medical School (MHH), we will investigate developmental, structural, and molecular alterations of bone and cartilage in spinal muscular atrophy (SMA). Patient-derived samples will be examined using high-resolution µCT, synchrotron imaging, and histology in collaboration with MHH, while UMG conducts complementary cellular and molecular studies, including treatment-response analyses with SMN-enhancing therapies. This integrated approach aims to clarify skeletal pathomechanisms in SMA and support improved therapeutic strategies.

  • Phd Student

    vor 2 Wochen

    Göttingen, Deutschland Institut für Herz- und Kreislaufphysiologie Vollzeit

    Ihre Aufgaben **Your tasks**: - work within in the team for optogenetic laryngeal pacemaking of the CRC1690 within the working group vegetative optogenetics in collaboration with the department for otorhinolaryngology - prepare the translation of optogenetic therapies into the clinics - obtain a PhD degree Ihre Qualifikationen **Your profile**: - labwork...

  • Phd Student

    vor 1 Tag

    Göttingen, Deutschland Institut für Herz- und Kreislaufphysiologie Vollzeit

    Ihre Aufgaben - Develop and optimize novel fluorescence microscopy tools to study ER-mitochondria contact sites in collaboration with chemistry partners - Investigate regulatory mechanisms of organellar contact sites using advanced imaging methods - Design and independently execute your research and manage your schedule - Remain up to date with current...

  • Phd Student

    vor 1 Tag

    Göttingen, Deutschland Universitätsmedizin Göttingen Vollzeit

    The University Medical Center Göttingen (UMG) unites the Medical Faculty of the Georg-August University and the University Hospital in an integration model. With around 9,700 employees, the UMG and its subsidiaries are one of the largest employers in the region. Our clinics and institutes stand for high-quality patient care, excellent research, modern...

  • PhD student position

    vor 1 Tag

    Göttingen, Deutschland Universitätsmedizin Göttingen UMG Vollzeit 40.000 € - 50.000 € pro Jahr

    Ihre Aufgabenwork within the platform 4) immune-phenotypingprepare the translation of optogenetic therapies into the clinicsobtain a PhD degreeIhre Qualifikationencompleted Master of Sciences or equivalent in a Life Sciences subject (biology, chemistry, physics,…)labwork experience (cloning, cell culture, transfection/transduction, FACS, immunostaining,...

  • PhD Student or Postdoc Position

    vor 2 Wochen

    Göttingen, Deutschland Max Planck Institute for Biophysical Chemistry Vollzeit

    PhD Student or Postdoc Position (f/m/d) Job Code: 24-25 Job Offer from August 22, 2025 The Max Planck Institute for Multidisciplinary Sciences is a leading international research institute of exceptional scientific breadth. With more than 40 research groups and some 1,000 employees from over 50 nations, it is the largest institute of the Max Planck...

  • Phd Student

    vor 24 Stunden

    Göttingen, Deutschland Universitätsmedizin Göttingen Vollzeit

    The University Medical Center Göttingen (UMG) unites the Medical Faculty of the Georg-August University and the University Hospital in an integration model. With around 9,700 employees, the UMG and its subsidiaries are one of the largest employers in the region. Our clinics and institutes stand for high-quality patient care, excellent research, modern...

  • PhD Student or Postdoc Position

    vor 2 Wochen

    Göttingen, Deutschland Max Planck Institute for Biophysical Chemistry Vollzeit

    PhD Student or Postdoc Position (f/m/d) function updateMastodonHref(event, link) { event.preventDefault(); let site = prompt("Geben Sie den Mastodon-Server ein, den Sie verwenden (z. B. mastodon.social):"); if (site) { try { let inputUrl; if (site.startsWith('http')) { inputUrl = new URL(site); inputUrl.protocol = "https:" } else { inputUrl = new...

  • Phd Students

    Vor 3 Tagen

    37073 Göttingen, Deutschland Georg-August-Universität Göttingen Vollzeit

    The _International Max Planck Research School (IMPRS) for Genome Science _is looking for **PhD Students **(M/F/d)** The IMPRS for Genome Science is a graduate program established as a cooperation between the University of Göttingen and several other research institutions at the Göttingen Campus, including the Max Planck Institutes. Our research school...

  • PhD-student (all genders welcome)

    vor 2 Wochen

    Göttingen, Deutschland Georg-August-Universität Göttingen Vollzeit 45.000 € - 55.000 € pro Jahr

    At the University of Göttingen -Public Law Foundation-, DNPW - Abt. Agrarentomologie, there is a position asPhD-student (all genders welcome)Entgeltgruppe 13 TV-L/65%to be filled. Starting date is 4/1/2026. The position is limited to 03/31/2030.Employment is subject to the final approval of project funding.Topic: "Influence of single & dual abiotic stress...

  • Phd Position

    Vor 6 Tagen

    Göttingen, Deutschland Universitätsmedizin Göttingen Vollzeit

    The University Medical Center Göttingen (UMG) unites the Medical Faculty of the Georg-August University and the University Hospital in an integration model. With around 9,700 employees, the UMG and its subsidiaries are one of the largest employers in the region. Our clinics and institutes stand for high-quality patient care, excellent research, modern...