Doctoral & Postdoctoral Positions in Computational

vor 1 Woche

Erlangen, Deutschland Friedrich-Alexander-Universität Erlangen-Nürnberg Vollzeit

**Doctoral & Postdoctoral Positions in Computational Membrane Biophysics in Erlangen**

Applications are invited for PhD positions/Postdoc/Senior Postdoc in our lab for theoretical and computa
- tional membrane biophysics at the Friedrich-Alexander University of Erlangen-Nürnberg, Germany.

Plasma membranes and in general biomembranes establish and maintain differences in composition between the cell or organelle interior and exterior. Biomembranes are the site for cell-cell recognition, they allow active and passive transport of material into and out of the cell, and they harbour proteins as initiators of signal transduction pathways.
Projects address the physico-chemical driving forces for the establishment of membrane domains within the immune cell plasma membrane, and their role for sensing of external signals by immune receptors and signal transduction, as well as membrane remodeling. The aim is to shed light on the cooperative action of proteins and lipids in shaping biomembrane structure.

Central questions for our research are
- How are external signals sensed by immune cells, how do lipids contribute to signal transfer across the cell membrane, and how do lipids modulate immune cell activation?
- What is the role of plasma membrane domains in immune cell activation?
- Can we modulate or control immune cell function by cell membrane composition? and more general
- What are the physical driving forces for membrane domain formation?
- How is domain formation linked to plasma membrane asymmetry?
- How are plasma membrane asymmetry and biological membrane processes interlinked?

**Applicants for doctoral positions**:
**Postdoc applicants**:
The successful applicant has a keen interest and strong skills in methods from statistical and computational physics, in particular atomistic and coarse-grained molecular dynamics simulations. The project involves close collaboration with immunology groups. The Postdoc will have the opportunity to participate in a research cluster studying the structure and function of immune domains.
- Other requirements: _
High level of English and good communication skills; effective team working.

Erlangen is a center for immunobiology with more than 70 groups focusing on immunological topics. In addition, since 2021, the University of Erlangen hosts a National High Performance Computing Center (hpc.fau.de) with a focus on atomistic simulations.

Prof. Dr. Rainer Böckmann
Computational Biology

Art der Stelle: Befristeter Vertrag, Vollzeit
Vertragsdauer: 36 Monate

Gehalt: 2.700,00€ - 3.200,00€ pro Monat

Arbeitszeiten:

- Montag bis Freitag

Leistungen:

- Betriebliche Altersvorsorge
- Betriebliche Weiterbildung
- Betriebsarzt
- Flexible Arbeitszeiten
- Kinderbetreuung

Ausbildung:

- Master (Erforderlich)

Sprache:

- Englisch (Erforderlich)

Arbeitsort: Ein Arbeitsort

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