Master Thesis

Vor 5 Tagen


Duesseldorf, Deutschland Forschungszentrum Jülich Vollzeit

As a leading research institution for microbial biotechnology the Institute of Bio

**Your Job**:
Quantifying the activity of enzymes operating within the large-scale biochemical network is a fundamental challenge in Systems Bio(tech)nology. Here, the unknown parameters must be inferred from models that are incomplete and data that involve errors. For such challenges, Bayesian analysis using Markov Chain Monte Carlo (MCMC) has become the gold standard.

In this project, you will bring MCMC methods into the setting of metabolic flux inference and, with inspiration from existing algorithms, develop tailored MCMC algorithms. You will implement the ensuing algorithms in an existing C++ framework, validate and benchmark them with a realistic case study.

The main focus of the project can develop either more in the mathematical theory of MCMC, the implementation of code for the Jülich supercomputers (GPU/CPU), or being combined with a practical modeling project.

**Your Profile**:

- You are highly motivated, with an interest in probability theory, mathematics, and data science.
- Very good practical C++ and Python programming skills allow you to make your ideas happen.
- You have strong interest in curiosity-driven multidisciplinary research.

**Our Offer**:
We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change

We support you in your work with:

- An interesting and socially relevant topic for your thesis with future-oriented themes
- Ideal conditions for gaining practical experience alongside your Master studies
- An interdisciplinary collaboration on projects in an international, committed and collegial team
- Excellent technical equipment and the newest technology
- Qualified supervision and support
- The chance to independently prepare and work on your tasks
- Flexible working hours as well as working location


  • Master Thesis

    vor 2 Wochen


    Duesseldorf, Deutschland Forschungszentrum Jülich Vollzeit

    The transformation of the energy sector is a major challenge of the 21st century. The Institute of Energy and Climate Research - Techno-economic Systems Analysis (IEK-3) uses large models to investigate the question of which technologies energy systems need to be composed in order to become both, cost-efficient and environmentally friendly. Become part of...


  • Duesseldorf, Deutschland Birkenstock Group B.V. & Co. KG Vollzeit

    BIRKENSTOCK is a global brand which embraces all consumers regardless of geography, gender, age and income. The company is deeply footed on a family tradition of shoemaking that can be traced back to 1774. With around 6200 employees worldwide, BIRKENSTOCK is the largest employer in the German footwear industry. To ensure our quality standards, we produce...

  • Master Thesis

    vor 1 Tag


    Duesseldorf, Deutschland Forschungszentrum Jülich Vollzeit

    The demand for environmental-friendly technologies is increasing significantly due to the depletion of natural resources and global pollution of the environment. In this regard, scientists from all over the world are struggling to invent technologies for “green” production of electronics that would be CO 2-neutral, not fuel-consuming, and fully...

  • Master Thesis

    vor 2 Wochen


    Duesseldorf, Deutschland Forschungszentrum Jülich Vollzeit

    The transformation of the energy sector is a major challenge of the 21st century. The Institute of Energy and Climate Research - Techno-economic Systems Analysis (IEK-3) uses large models to investigate the question, of which technologies energy systems need to be composed in order to become both, cost-efficient and environmentally friendly. Become part of...

  • Master Thesis

    vor 2 Wochen


    Duesseldorf, Deutschland Forschungszentrum Jülich Vollzeit

    Two-terminal perovskite-silicon tandem solar cells are showing great promise to become the dominant commercial photovoltaic technology in the future, with the highest laboratory efficiency being 33.9% for a 1 cm x cm device. Further development in the efficiency of these devices is limited by the low fill factor, due to resistive losses arising from the low...


  • Duesseldorf, Deutschland IUF - Leibniz-Institut für umweltmedizinische Forschung GmbH Vollzeit

    The working group “Alternative method development for environmental toxicity testing” led by Prof. Ellen Fritsche is looking for a student (f/m/d) for a Master Thesis with the title: **The project**: Human brain development is a complex series of neurodevelopmental processes sensitive to harmful chemicals. In this project, you will be part of the current...


  • Duesseldorf, Deutschland SMS group GmbH Düsseldorf Vollzeit

    SMS group is noted worldwide for its mechanical and plant engineering expertise, its future-oriented technologies and its excellent service for the metals industry. We use our 150 years of experience and our digital know-how to provide the industry continuously with innovative products and processes - even outside our core business. We are the partner for...

  • Master Thesis

    Vor 5 Tagen


    Duesseldorf, Deutschland Forschungszentrum Jülich Vollzeit

    As a leading research institution for microbial biotechnology the Institute of Bio - and Geosciences - Biotechnology (IBG-1) focuses on the development of biotechnological processes for the sustainable bio-based production of pharmaceutical and chemical products. We investigate how microorganisms and isolated enzymes can be used to produce a variety of...


  • Duesseldorf, Deutschland Forschungszentrum Jülich Vollzeit

    The Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons (ER-C) operates as a centre of excellence and national user facility, in which the structure and properties of materials can be revealed on the atomic scale using the world’s most powerful and versatile transmission electron microscopes. The materials that can be studied range from...


  • Duesseldorf, Deutschland IUF - Leibniz-Institut für umweltmedizinische Forschung GmbH Vollzeit

    The working group of “Alternative method development for environmental toxicity testing” led by Prof. Ellen Fritsche is looking for a student (f/m/d) for a Master Thesis with the title: **Establishment of a protocol and test method for primitive hematopoiesis based on human induced pluripotent stem cells (hiPSC) for developmental immunotoxicity testing...