Master Thesis
Vor 5 Tagen
As a leading research institution for microbial biotechnology the Institute of Bio
**Your Job**:
Quantifying the activity of enzymes operating within the large-scale biochemical network is a fundamental challenge in Systems Bio(tech)nology. Here, the unknown parameters must be inferred from models that are incomplete and data that involve errors. For such challenges, Bayesian analysis using Markov Chain Monte Carlo (MCMC) has become the gold standard.
In this project, you will bring MCMC methods into the setting of metabolic flux inference and, with inspiration from existing algorithms, develop tailored MCMC algorithms. You will implement the ensuing algorithms in an existing C++ framework, validate and benchmark them with a realistic case study.
The main focus of the project can develop either more in the mathematical theory of MCMC, the implementation of code for the Jülich supercomputers (GPU/CPU), or being combined with a practical modeling project.
**Your Profile**:
- You are highly motivated, with an interest in probability theory, mathematics, and data science.
- Very good practical C++ and Python programming skills allow you to make your ideas happen.
- You have strong interest in curiosity-driven multidisciplinary research.
**Our Offer**:
We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change
We support you in your work with:
- An interesting and socially relevant topic for your thesis with future-oriented themes
- Ideal conditions for gaining practical experience alongside your Master studies
- An interdisciplinary collaboration on projects in an international, committed and collegial team
- Excellent technical equipment and the newest technology
- Qualified supervision and support
- The chance to independently prepare and work on your tasks
- Flexible working hours as well as working location
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