Scientist, Phd Student

vor 2 Wochen

Magdeburg, Deutschland Leibniz-Institut für Neurobiologie Vollzeit

The Leibniz Institute for Neurobiology (LIN) is an internationally recognized neuroscientific research institute and dedicated to the research on learning and memory. Our research comprises all organizational levels of the brain - from molecular and cellular processes to complex neuronal networks and behavior.

**Scientist, PhD student (f/m/d) on the neural basis of memory (neurosciences)**

The department focuses on dissociating the contribution of different medial temporal lobe areas such as CA1, CA3, DG, MEC, LEC, PrC, POR to memory in health, aging and in animal models of amnesia. Memory for time, space and episodes as well as the consolidation and reconsolidation of memory are studied. Within this frame, the FAM has recently identified new spatial and non-spatial subnetworks segregated along the proximodistal axis of the hippocampus (Nakamura et al, J. Neuroscience, 2013; Beer and Vavra et al, Plos biology, 2018; Ku et al, Cell Reports, 2024), hypothesized a network shift between the Trisynaptic loop and the Temporoamonic pathways for the retrieval of memories as they age (Lux et al, Elife, 2016; Atucha et al, Cell Reports, 2023) and depicted memory networks supporting memory reconsolidation (Lux et al, Cerebral cortex, 2017). Techniques include high-order standard or translational humans to rats memory tasks (Sauvage et al, Nature Neuroscience, 2008) combined with lesions, optogenetics, high-resolution molecular imaging based on the detection of IEG and in-vivo electrophysiology. fMRI studies in awake rodents (9.4T) and human behavioral studies are also conducted to a lesser extent.

**About the project**:The SFB 1436 subprojectB07 investigates circuit-specific improvements of spatial and non-spatial memory involving entorhino-hippocampal subnetworks. The project includes optogenetic manipulations, immediate-early gene (IEG) imaging based on in-situ hybridization, in-vivo electrophysiology data analysis with mice and is tightly linked to independent subprojects involving in-vivo electrophysiology in humans and high-resolution fMRI in awake rats.

The communication language of the lab is English. The group interacts tightly with the Research Group Cognitive Neurophysiology (PI M. Yoshida; in-vitro/in vivo electrophysiology & computational neurosciences) as well as with national and international partners including S. Tonegawa (Boston, USA), J. Csicsvari (IST, Austria), E. Düzel (DZNE Magdeburg, Germany) and M. Höhn (MPI Cologne, Germany).

**Your profile**:

- MSc in Neurosciences, Life sciences or related fields
- Experience in behavioural and molecular techniques
- Programing experience (Matlab and/or python)
- willingness to work with animal models
- general interest in interspecies / interdisciplinary studies

**Job Type**: Part-time

Pay: Up to 37.510,00€ per year

**Language**:

- English (required)

Work Location: In person

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