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Phd-student in
Vor 7 Tagen
Göttingen, Deutschland Universitätsmedizin Göttingen VollzeitThe University Medical Center Göttingen (UMG) unites the Medical Faculty of the Georg-August University and the University Hospital in an integration model. With around 9,700 employees, the UMG and its subsidiaries are one of the largest employers in the region. Our clinics and institutes stand for high-quality patient care, excellent research, modern...
Phd Position
vor 2 Wochen
Ihre Aufgaben
- Work in a stimulating, international and collaborative environment
- Drive and develop your own research project
- Being part of an active collaborative environment within the priority programme SPP2453 and the Göttingen campus
- “Hands on work” on a broad spectrum of state of the arts methods in biochemistry, molecular
- and cell biology, dataset analysis
- Present research results during national and international scientific conferences
Ihre Qualifikationen
- You are a motivated and enthusiastic scientist who can work independently but also in a team
- Fluent English language skills (written and spoken) are required
Wir bieten
- The project will be integrated into the priority programme “Integration of mitochondria into the cellular proteostasis network” (SPP 2453)
- You will work in a high-impact research field embedded in the collaborative environment of the Göttingen Campus including several supportive facilities and inspiring research consortia
- Within the SPP2453 you will collaborate with different research groups in Germany
- Fixed termed position (65%) for 3 years, salary will be in accordance to the German Public Sector Collective Agreement (TV-L)
- Starting date: as soon as possible
Einleitungstext
Mitochondria are crucial for many functions within the cell and essential for the viability of nearly all eukaryotes. As mitochondria have originally been investigated as solely entities within a cell, they are now considered as part of an active metabolic network together with other organelles. Our group is located in the Department of Cellular Biochemistry at the University Medical Center Göttingen. The goal of our research is to understand how mitochondria are integrated into the cellular network to fulfil manifold functions such as ATP production or reactive oxygen species (ROS) generation. To do so, mitochondria rely on the biogenesis and maintenance of the mitochondrial proteome of which 99% is nuclear encoded. Hence, we aim to understand i) how mitochondrial functions influence cytosolic protein synthesis; ii) how they maintain a permanent functional import pathways for newly synthesized proteins and iii) which save-guarding mechanisms are in place to keep mitochondrial import running.
To address this, we are integrated into the priority programme SPP2453 of the German Research Foundation (Deutsche Forschungsgesellschaft, DFG), where we with our collaborators combine biochemical and cell biology approaches with high resolution mass spectrometry and the analysis of cytosolic quality control prozesses.
Göttingen is an international student city located in the center of Germany, where besides the University and University Medical Center a number of renowned institutes such as the Max Planck Institute for Multidisciplinary Sciences are located, providing a stimulating collaborative environment.
