Technical Assistant, Upstream Processing
vor 1 Woche
Location: Planegg, Germany
Type: Full-time, Perm
Reporting to: Senior Manager of Upstream Processing
About Ascend:
Ascend is a new model for gene & cell therapy design, development, and manufacturing. We partner with ambitious biotechnology teams to embed scalable manufacturing in their operations from the beginning. We support manufacturing and process development projects from design through to clinical and commercial scale.
**Requirements**:
- Production of recombinant gene therapy AAV on a benchtop scale using Ascend's own process platform (USP)
- Development of new processes for the production of rAAV with eukaryotic cells in suspension cultivation systems
- Carrying out process-relevant analysis to determine the qualitative and quantitative properties of the rAAV produced through characterization of samples (e.g. ELISA, qPCR, SDS-PAGE, DLS)
- Independent planning, implementation, evaluation and documentation of experiments
- Trains and technically supervises other TAs
- Write and collate experiment data and reports as well present them
- Creation of work instructions and protocols and other relevant technical documents
- Assumption of device responsibilities as well as general tasks to maintain daily laboratory operations
**Requirements**:
- Completed training to become a BTA, MTA, CTA, ATA, chemical laboratory assistant, Bachelor of Science (B. Sc) or comparable qualification
- You have in-depth practical experience in the field of eukaryotic cell culture in the bioreactor
- You have already worked on the production of recombinant viral vectors on a laboratory scale
- Routine handling of molecular biological and protein biochemical techniques such as qPCR, ELISA, SDS-PAGE
- Pronounced quality awareness and organizational talent with regard to the planning, implementation and documentation of experiments
- You have a good command of English and a good command of MS Office
- The attitude that big goals can only be achieved as a team
- The motivation to contribute through your own work to make gene therapies accessible to patients
**Benefits**
As well as a competitive salary, fantastic professional development opportunities and career progression we offer:
- Performance-based bonus
- Pension scheme
- Share scheme
- More to come as we grow
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