Researcher in AI-Driven Protein Therapeutics for Cancer Pathways

Your Job:The current position is a part of the Helmholtz Bioengineering Consortium, including generative AI experts, structural and molecular biologists and clinicians to develop anticancer therapeutics by protein design. This project will apply cutting-edge generative AI methods—including protein design, structure–function prediction, and multimodal learning—to develop and optimize a new generation of protein therapeutics that can overcome resistance mechanisms in cancer pathways. Specific objectives include: Identifying protein modalities most predictive and functionally relevant to the EGFR–Ras signaling cascade Developing generative AI models for protein design within an existing multimodal framework integrating sequence, structure, functional, microscopy and molecular dynamics data Incorporating reinforcement learning strategies to guide model optimization, with a focus on minimizing immune responses and improving therapeutic viabilityYour Profile: Completed Master/PhD Degree in the field of computer science, biology, physics, mathematics or a related field Programming skills in Python required (Numpy, Pandas, Scikit-learn, Pytorch) Hands-on experience in Deep Learning Demonstrated interest in working with biological data; practical experience is a plus Willingness to learn and ability to think outside the box Independent and responsible way of working Excellent command of written and spoken English A PhD degree is not a prerequisite for application. Opportunities to pursue a PhD in this subject area are available during employment.Our Offer:We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change We support you in your work with: MEANINGFUL TASKS: An exciting opportunity to explore a biologically and clinically meaningful topic with opportunities for translation and potential commercialization. TEAM & ENVIRONMENT: You will work in a motivated team with an international and interdisciplinary focus – at one of the largest research institutions in Europe VACATION: You will receive 30 days of vacation plus additional days off ( between Christmas and New Year`s) KNOWLEDGE & FURTHER TRAINING: Your professional development is important to us – we provide targeted, individual support HEALTH & WELL-BEING: Your health is important to us. You can look forward to a comprehensive occupational health management program with a wide range of offerings - , a beach volleyball court, running groups, yoga classes, and much more. In addition, our company medical service and an experienced social counseling team are available to assist you on site WORK-LIFE BALANCE: Optimal conditions for balancing work and private life, as well as a family-friendly company policy. The option of flexible working (in terms of location) is generally available after consultation and in line with upcoming tasks and (on-site) appointments FAIR REMUNERATION: Depending on your existing qualifications and the tasks assigned to you, you will be classified in pay grade 13 of the TVöD-Bund (Collective Agreement for the Public Service). All information on the TVöD-Bund collective agreement can be found on the BMI website: . The monthly salaries in euros can be found on page 69 of the PDF download FIXED-TERM: The position is initially limited to 2 years In addition to exciting tasks and a collegial working environment, we offer you much more: We welcome applications from people with diverse backgrounds, in terms of age, gender, disability, sexual orientation / identity, and social, ethnic and religious origin. A diverse and inclusive working environment with equal opportunities in which everyone can realize their potential is important to us. The following links provide further information on diversity and equal opportunities: and on specific support options: We look forward to receiving your application. The job will be advertised until the position has been successfully filled. You should therefore submit your application as soon as possible.Apply nowContact formIf your questions have not yet been answered via our FAQs , please send us a message via our contact form.Please note that for technical reasons we cannot accept applications by e-mail.