Senior scientific software developer for AI in regulatory genomics

Vor 5 Tagen


Munich, Bayern, Deutschland Technical University of Munich Vollzeit

Senior scientific software developer for AI in regulatory genomics

18.03., Wissenschaftliches Personal

About us

The Chair of Computational Molecular Medicine, led by Prof Julien Gagneur, develops computational approaches to study the genetic basis of gene regulation and its implication in diseases. Applications of our work range from understanding basic mechanisms governing gene expression to unraveling genetic aberrations triggering rare diseases and cancer. More at

The project

EPIC is a 10-million Euro project funded for 6 years by the European Research Council under the ERC Synergy grant scheme. EPIC brings together 3 groups at the edge of complementary technologies – Vicente Pelechano (Karolinska Institute) for the development of high-throughput omics assays, Kevin Verstrepen (VIB-KU Leuven) for synthetic biology, and Julien Gagneur for the AI and bioinformatics. EPIC aims at deciphering the complete regulatory code, from chromatin to protein abundance, of the eukaryote S. cerevisiae. To this end, EPIC takes a unique strategy to study gene regulation by leveraging evolution. We will assay fungal species spanning hundreds of millions of years across all layers of gene regulation and under different growth conditions. Moreover, EPIC will design nearly a million sequences to systematically test and refine our model of the regulatory code and eventually design genes and cells for biotechnological applications. Our research group will develop new AI modeling paradigms to learn from such multi-modal and multi-species data effectively. This will allow us to unravel complex regulatory instructions and their evolution, build predictive models, and design genes with intended regulation.

Your role

As the senior computational biologist of the team, your role is to ensure a robust and scalable ecosystem for the entire project, covering, the design and implementation of:
* the data backend
* automated processing workflows including QC and reproducibility metrics
* APIs and packages supporting the development of new algorithms spanning large * language modeling of DNA and RNA sequences, and algorithms for MPRA and gene design
* the project data portal to browse data and model outputs
* You will interact with other postdocs and be supported by more junior colleagues (PhD candidates, Bachelor's and Master's students).

Requirements

* PhD degree in Computational biology or related (Computer Science, Physics) or at least 3 years of experience in scientific software development
* Experience with NGS data processing and modeling
* Experience with deep learning frameworks
* Scientific software development
* Excellent organizational skills and good mentoring capabilities
* Fluent in English. Can communicate clearly in a multidisciplinary collaborative setting

We offer

The position can start on July,1st . It is funded until June, 31st
Salary according to the TV-L (German academic salary scale) - E14, the highest salary scale before group leader. It includes social benefits (healthcare, pension, and unemployment insurance)
Possibility to develop research management skills and move to an open-end position
International, attractive, and interdisciplinary working environment. The TUM CS department, among the top-ranked in Europe, gives access to excellent colleagues and students
Flexible working hours and home-officing policy
Disabled applicants with equal suitability and qualification will be given particular consideration
The TUM is striving to increase the proportion of women and hence applications from women are therefore expressly welcomed

Application
Applications should include a cover letter, CV, transcripts, and references and must be sent to by Sunday, April 14th referring to "EPIC - Postdoc 1" in the email title. We process and store your application files in accordance to the Art. 13 General Data Protection Regulation (GDPR) for the collection and processing of personal data (scroll down for the English version). By submitting your application, you confirm that you have read TUM's data protection information.

Die Stelle ist für die Besetzung mit schwerbehinderten Menschen geeignet. Schwerbehinderte Bewerberinnen und Bewerber werden bei ansonsten im wesentlichen gleicher Eignung, Befähigung und fachlicher Leistung bevorzugt eingestellt.

Hinweis zum Datenschutz:
Im Rahmen Ihrer



  • Munich, Bayern, Deutschland ExoMatter Vollzeit

    We are looking for an exceptional individual to join ExoMatter as a Senior Scientific Developer. In this role, you will be responsible for managing the intersection between software engineering and the scientific research within our company to further develop our Materials R&D platform.Become part of a young deep tech and software startup based in Munich and...

  • Senior AI Developer

    vor 2 Wochen


    Munich, Bayern, Deutschland Impower Vollzeit

    Are you looking to haveFREEDOM - GROWTH - IMPACTThen let's revolutionize the future of property management with our uniquely simple, fast and beautiful PropTech solution:IMPOWERToday, 110,000 people manage around 15 million properties with highly complex processes, but with paper and outdated technology.Impower was founded in 2019 with a single mission:To...

  • Senior Project Manager

    vor 3 Wochen


    Munich, Bayern, Deutschland NFON Vollzeit

    The roleWe are seeking an experienced and highly motivated Senior Project Manager to lead our internal AI community initiatives and facilitate strategic customer and partner feedback projects. In this role, you will foster a culture of AI learning and innovation, ensuring compliance with the EU AI Act while enabling skill development tailored to different...


  • Munich, Bayern, Deutschland QNX Software Systems Vollzeit

    Worker Sub-Type:Regular Job Description: BlackBerry QNX is a trusted supplier of safe and secure operating systems, hypervisors, frameworks and development tools, and provides expert support and services for building the world's most critical embedded systems. We are the embedded experts. BlackBerry QNX was born in embedded, and provides time-tested and...


  • Munich, Bayern, Deutschland NumberSquare GmbH Vollzeit

    Location: Germany (remote and Munich)Start Date: January 2025Contract Type: Full-timeThis job posting is on behalf of one of our partner companies (Jessy Works), an innovative startup that is shaping the future of AI.Do you already think about the AI of TOMORROW and love the FREEDOM of working for a fast-growing tech start-up? Then we look forward to turning...

  • AI Engineer, Germany

    vor 3 Wochen


    Munich, Bayern, Deutschland Boston Consulting Group Vollzeit

    Locations: München | Berlin | FrankfurtWho We AreBoston Consulting Group partners with leaders in business and society to tackle their most important challenges and capture their greatest opportunities. BCG was the pioneer in business strategy when it was founded in 1963. Today, we help clients with total transformation inspiring complex change, enabling...

  • AI Engineer, Germany

    vor 2 Wochen


    Munich, Bayern, Deutschland Boston Consulting Group Vollzeit

    *Locations*: München | Berlin | FrankfurtWho We AreBoston Consulting Group partners with leaders in business and society to tackle their most important challenges and capture their greatest opportunities. BCG was the pioneer in business strategy when it was founded in 1963. Today, we help clients with total transformation-inspiring complex change, enabling...


  • Munich, Bayern, Deutschland Sono Motors GmbH Vollzeit

    Your TasksJoin our dynamic data team responsible for the entire data value chain of our solar solutions from logging data on the vehicle to presenting valuable results within numerous productsDevelop and maintain our software infrastructure for telematics integration, data analytics, and simulation projectsContribute to improving both front-end and back-end...


  • Munich, Bayern, Deutschland Avo Intelligence Vollzeit

    We are seeking an Edge AI & Embedded ML Engineer to develop high-performance, low-latency AI models for deployment on resource-constrained devices. This role involves optimizing deep learning models for real-time inference on edge hardware, ensuring efficiency in power-limited environments.If you have experience with TinyML, on-device AI, and embedded neural...


  • Munich, Bayern, Deutschland ATOSS Software AG Vollzeit

    Senior Machine Learning Engineer m/f/d Munich | full time | unlimited Your responsibilities: Design, develop, and deploy scalable AI and machine learning models for internal and customer use cases Collaborate with cross-functional teams to integrate AI solutions into existing products. Collaborate with cross-functional teams to Integrate and...

  • Applied AI Researcher

    vor 17 Stunden


    Munich, Bayern, Deutschland appliedAI Vollzeit

    About usAI is a powerful technology reshaping society, but it also presents complex challenges. The appliedAI Institute for Europe stands for Trustworthy AI by focusing on fairness, transparency, and accountability to ensure AI driven innovation while respecting ethical standards. As a central harbour in the European AI ecosystem, we provide knowledge,...

  • Applied AI Researcher

    Vor 4 Tagen


    Munich, Bayern, Deutschland appliedAI Vollzeit

    About usAI is a powerful technology reshaping society, but it also presents complex challenges. The appliedAI Institute for Europe stands for Trustworthy AI by focusing on fairness, transparency, and accountability to ensure AI driven innovation while respecting ethical standards. As a central harbour in the European AI ecosystem, we provide knowledge,...

  • Senior Software Developer

    vor 16 Stunden


    Munich, Bayern, Deutschland Randstad Deutschland Vollzeit

    Our Client Johnson & Johnson has a vacant position as a Senior UI Software Engineer 100% remote. Tariff-based wages, care by a company medical center, and employee discounts - all advantages that you can count on with Randstad. It's best to apply online right away and secure this job Implement and maintain UI based on extensive UX studies and detailed UI...


  • Munich, Bayern, Deutschland mousebouncer GmbH Vollzeit

    ZeroMOUSE is an AI-powered device made in Germany that prevents cats from bringing prey, such as mice or birds, into the house. It seamlessly integrates with various microchip cat flaps and offers features like night vision and detailed tracking of blocked entry attempts. We are looking for a Junior Software Developer to join our engineering team in...

  • Head of AI

    vor 1 Woche


    Munich, Bayern, Deutschland Congrify Vollzeit

    At Congrify we are a payments data observability and intelligence company.We enable merchants and payment service providers increasing revenues, optimizing costs, ensuring compliant and efficient reconciliation processes.Payment professionals can free up their time without needing to spend hours in bringing together data from multiple payment service...


  • Munich, Bayern, Deutschland Flughafen München Vollzeit

    Zum nächstmöglichen Zeitpunkt suchen wir dich als Senior SAP Software Developer (w/m/d)Neue Herausforderungen in den Bereichen Digitalisierung, Cloud und S/4HANA fordern neue Entwicklungsumgebungen, Konzepte und deren technische Umsetzung im SAP-Umfeld. Werde ein zentraler Teil dieser digitalen Transformation und unterstütze unser SAP Competence Center...


  • Munich, Bayern, Deutschland m2TALENTS Vollzeit

    Shape the Future of Software Development Are you an experienced Java Developer looking for a role that combines technical challenges, autonomy, and career growth? Join a fast-growing, innovative IT studio that creates cutting-edge solutions for startups and enterprise clients. Work directly with the CEO and a talented team to develop high-impact projects...


  • Munich, Bayern, Deutschland Ki Reply GmbH Vollzeit

    Reply ist auf die Entwicklung und Einführung von Lösungen auf Basis neuer Kommunikationskanäle und digitaler Medien spezialisiert. Mit seinem Netzwerk aus hochspezialisierten Unternehmen unterstützt Reply die europäischen Branchenführer aus Telekommunikation und Medien, Industrie und Dienstleistung, Banken und Versicherungen sowie öffentliche...


  • Munich, Bayern, Deutschland DeepOpinion Vollzeit

    Your missionDeepOpinion is the enterprise-grade Agentic Automation platform enabling teams to put their complex knowledge work on autopilot. By combining Agentic AI, business process digitization and no-code development in a single platform, teams can create AI apps in minutes to achieve 90%+ straight-through processing.With €11 million raised in a Series...


  • Munich, Bayern, Deutschland Boston Consulting Group Vollzeit

    Locations : München Berlin Frankfurt Who We Are Boston Consulting Group partners with leaders in business and society to tackle their most important challenges and capture their greatest opportunities. BCG was the pioneer in business strategy when it was founded in 1963. Today, we help clients with total transformation-inspiring complex change, enabling...