Senior Research Scientist
vor 4 Wochen
Job Description:
As a Senior Research Scientist at Robert Bosch Centrum für Tumorerkrankungen, you will be responsible for utilizing modern sequencing-based molecular biology approaches to examine transcriptomic and gene regulatory mechanisms controlling tumor- and senescent cell identity and therapy response.
Key Responsibilities:
- Design and execute experiments to investigate gene regulatory mechanisms in primary tumor tissue using multiplex immunofluorescence staining and multispectral imaging.
- Perform bioinformatic analyses and interpretation of data to perform hypothesis testing and generation.
- Prepare histological samples for single cell RNA-sequencing using the 10X Genomics technology.
- Conduct advanced cell culture experiments to examine the effects of drug treatment in various translational model systems.
- Collaborate with internal or external research teams to advance research goals.
- Document work procedures, data acquisition, and analyses.
Requirements:
- Master of Science in a related field (biology, molecular biology, biotechnology, bioinformatics or similar)
- Experience with cell culture, transfections, stainings, and molecular biology techniques
- Extensive experience with bioinformatic analyses (R, Python)
- Strong work ethic and high level of self-motivation
- Ability to work independently and as part of a team
- Confident written and spoken English skills
What We Offer:
- An exciting and international research environment
- Excellent experience and expertise in modern epigenetic methods
- Outstanding bioinformatic expertise
- Extensive modern infrastructure for all methods related to the project
- Collaborative team environment with mutual appreciation and support
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