Senior Research Scientist

vor 4 Wochen


Stuttgart, Baden-Württemberg, Deutschland Robert Bosch Centrum für Tumorerkrankungen Vollzeit

Job Description:

As a Senior Research Scientist at Robert Bosch Centrum für Tumorerkrankungen, you will be responsible for utilizing modern sequencing-based molecular biology approaches to examine transcriptomic and gene regulatory mechanisms controlling tumor- and senescent cell identity and therapy response.

Key Responsibilities:

  • Design and execute experiments to investigate gene regulatory mechanisms in primary tumor tissue using multiplex immunofluorescence staining and multispectral imaging.
  • Perform bioinformatic analyses and interpretation of data to perform hypothesis testing and generation.
  • Prepare histological samples for single cell RNA-sequencing using the 10X Genomics technology.
  • Conduct advanced cell culture experiments to examine the effects of drug treatment in various translational model systems.
  • Collaborate with internal or external research teams to advance research goals.
  • Document work procedures, data acquisition, and analyses.

Requirements:

  • Master of Science in a related field (biology, molecular biology, biotechnology, bioinformatics or similar)
  • Experience with cell culture, transfections, stainings, and molecular biology techniques
  • Extensive experience with bioinformatic analyses (R, Python)
  • Strong work ethic and high level of self-motivation
  • Ability to work independently and as part of a team
  • Confident written and spoken English skills

What We Offer:

  • An exciting and international research environment
  • Excellent experience and expertise in modern epigenetic methods
  • Outstanding bioinformatic expertise
  • Extensive modern infrastructure for all methods related to the project
  • Collaborative team environment with mutual appreciation and support


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