Structural Biology Research Fellow

vor 1 Monat


Heidelberg, Baden-Württemberg, Deutschland Embl-Ebi Vollzeit

Research Opportunity

The Embl-Ebi laboratory is seeking a highly motivated Postdoctoral Fellow to join our team in the field of structural biology and chromatin evolution. The successful candidate will work on a cutting-edge experimental research project focused on the structure-function analysis of chromatin in archaea.

Project Overview

The project aims to understand how eukaryotes evolved histone tails and tail-based regulatory mechanisms from an archaeal ancestor. The candidate will investigate the structural and functional effects of merging tail-less histones of a model archaeon with selected eukaryotic or Asgard histone tails in vitro and in vivo.

Key Responsibilities

  • Conduct biochemistry, biophysics, and structural biology experiments
  • Analyze cryo-EM single particle data and perform cryo-electron tomography
  • Collaborate with the laboratory of Naomichi Takemata (Kyoto University)

Requirements

  • PhD in structural biology, molecular biology, biochemistry, or related disciplines
  • Experience in cryo-EM/cryo-ET data acquisition and processing
  • Confidence in working via command line

What We Offer

  • 3-year contract
  • €4,010 per month stipend


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