Senior DMPK Expert

vor 4 Wochen


Grafing bei München, Bayern, Deutschland Nuvisan GmbH Vollzeit

We are seeking a highly skilled and experienced DMPK expert to join our team at Nuvisan GmbH. As a key member of our Pharmacokinetic Sciences group, you will provide scientific input into drug discovery and development programs for our clients.

Your responsibilities will include providing DMPK consultancy for new chemical entities and guiding pharmaceutical clients throughout different phases of the R&D value chain. You will assess PK/PD relationships in pre-clinical models, predict human PK parameters, dose, and dosing regimens, and provide scientific input to the design of in vitro and/or in vivo DMPK studies.

You will also perform gap analyses of DMPK discovery and/or development packages, conduct non-compartmental analyses (NCA) for PK and toxicokinetic studies, and write DMPK sections of regulatory dossiers (IND, IMPD) and Briefing Books.

As a DMPK representative in client project teams, you will design and commission PK experiments to support compound optimization, drug candidate selection, and/or subsequent development. You will also act as project manager and client contact for phase projects, overseeing in vitro and in vivo DMPK, bioanalytical, and toxicokinetic studies performed by Nuvisan.

To be successful in this role, you will have a PhD in pharmacy, biochemistry, chemistry, or a related field with relevant DMPK experience in the pharmaceutical, biotech industry, or at CROs. You will also have profound knowledge of the drug discovery and development process and how DMPK studies contribute to that.

Excellent interpersonal and communication skills, a strong customer focus, and very good English language skills are essential for this position. Problem-solving attitude and high personal initiative are also required.


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