Senior Research Scientist in Molecular Biology
vor 3 Wochen
Research Opportunity:
We are seeking a highly motivated postdoctoral researcher to join our team at the Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics. The successful candidate will investigate a novel molecular switch controlling thrombo-inflammation based on the interaction of TF (F3, tissue factor) and interferon-alpha receptor subunit 1 (IFNAR1) using cell biological, protein biochemical and in vivo approaches.
Scope of the Position:
The postdoctoral researcher will study the regulation of TF-IFNAR1 interaction and intracellular signaling in vitro and in vivo. We will use advanced in vitro methods, various omics approaches and innovative mouse models. Detailed structure-function analyses based on newly generated structural data will be performed to define the molecular mechanisms as a basis for innovative diagnostic and therapeutic approaches.
Requirements:
Applicants must have a Ph.D. in a biomedical field (biology, biochemistry, biotechnology, physiology, or equivalent), a strong publication record that will allow them to obtain independent funding, and prior experience with at least some of the methodological topics of this project: work with mice, molecular biology, protein biochemistry, flow cytometry, microscopy, immunohistochemistry. Experience in thrombosis & hemostasis and/or thrombo-inflammation is desirable.
Research Environment:
The successful candidate will join a highly collaborative institute and will have access to state-of-the-art facilities for molecular biology, protein biochemistry, biophysics, pharmacology, mouse genetics, and the latest imaging applications including light sheet and FRET microscopy. The position will be embedded in the ERC-funded project TameThiFlame. The Medical Faculty is located within the University of Leipzig with direct access to numerous research facilities of the University and extramural institutes such as the Helmholtz, Max Planck and Fraunhofer Institutes.
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Halle, Sachsen-Anhalt, Deutschland Universität Leipzig, Medizinische Fakultät VollzeitPhD Position in Molecular SwitchesResearch OpportunityWe are seeking a highly motivated and skilled researcher to investigate a novel molecular switch controlling thrombo-inflammation. The successful candidate will study the regulation of TF-IFNAR1 interaction and intracellular signaling in vitro and in vivo using advanced in vitro methods, various omics...
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