Postdoctoral Researcher

University Hospital Würzburg - Clinical Genetics and Genomedicine
- as soon as possible
- Full-time, Part-time
- Fixed-Term
- Application deadline: 13/12/2024_

Join **University Hospital Würzburg** as a **Postdoctoral Researcher (M/F/d) **in our cutting-edge research on genomic, transcriptomic, and epigenomic alterations in childhood cancers. We are seeking a passionate and driven Postdoctoral Scientist to support our projects, focusing on immunoregulatory mechanisms in childhood cancer dysregulation.

Successful applicant will study interactions between immune and leukemic cells, and explore the developmental origins, heterogeneity, and the plasticity of leukemic cells, using multi-omic single-cell sequencing techniques, specifically scRNA-Seq and scATAC-Seq. The aim of the project is to improve our understanding of relapse-driving mechanisms in leukemia, and aid in identification of potential biomarkers, or therapeutic targets, in order to improve patient risk-stratification and identify new treatment strategies.

**We offer**:

- A dynamic, **multidisciplinary research group** with ample opportunities for professional growth, so you can expand your skillset.
- The **opportunity to establish your own career path within the research field**, ensuring long-term career development.
- ** National and international lab exchange opportunities**, allowing you to broaden your professional network.
- ** Flexible working hours** and a family-friendly environment, helping you balance personal and professional life.
- ** Excellent employee benefits**, including sports and healthcare workshops, an attractive occupational pension, and a subsidized canteen, to enhance your overall well-being.

**Your Tasks**:

- Perform single-cell analysis (primarily multiome) to identify functionally relevant regions and associated genes.
- Analyze and evaluate large genetic, epigenetic, and clinical data sets for the study of childhood cancer immunoregulatory mechanisms.
- Integrate research findings with clinical data to develop novel biomarkers and diagnostic assays for clinical use.
- Collaborate with a multidisciplinary team of clinicians and scientists to translate research from bench to bedside.
- Coordinate the DKH-funded project, "Understanding and Preventing Relapse in Children with Acute Lymphoblastic Leukemia."

**Your Profile**:

- PhD in Biochemistry, Biology, Molecular Medicine, or related fields.
- Strong background in molecular biology.
- Experience in establishing novel molecular methods.
- Highly motivated, reliable, and able to work independently.
- Strong written and oral communication skills in English and German.
- Enthusiasm for interdisciplinary collaboration and communication.

This position is initially limited to 3 years with the potential for extension. Part-time work is possible. Compensation will be based on the Collective Agreement for Federal States (TV-L), depending on your qualifications and experience.

**This is what you can look forward to**:

- Training and Continuing Education
- Retirement Pension Plan
- Flexible Working Hours
- Collegiality
- Sport and Fitness Options
- Employee Events
- Corporate Benefits
- _

**_Univ.Prof. Dr. med. Anke Katharina Bergmann_**:

- Lehrstuhlinhaberin_
- Tel: +49931 201 29900_

In the case of a university degree from a non-EU country, a long version of the certificate evaluation from the Central Office for Foreign Education is required.

Remuneration is in accordance with the relevant collective agreements. Severely disabled applicants will be given preference if they are otherwise equally qualified.

The **University Hospital of Würzburg (UKW)** offers an innovative and excellent working environment in cutting-edge medicine. Here, employees benefit from state-of-the-art technology, extensive training and career opportunities as well as flexible working time models for an optimal work-life balance. We attach great importance to diversity and inclusion in order to create a respectful and supportive working environment. A strong sense of community and interdisciplinary collaboration are central to our way of working. Würzburg, a city with a high quality of life, offers a wide range of cultural and leisure activities as well as excellent educational opportunities. The UKW takes responsibility for the health of society and promotes an environment that focuses on ethical values and social commitment. Become part of our team and help shape the future of medicine.