Computational Biology Lead

vor 2 Wochen

Berlin, Deutschland Bayer Vollzeit

**At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where ,Health for all, Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining ‘impossible’. There are so many reasons to join us. If you’re hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there’s only one choice.**

**Computational Biology Lead - Preclinical Analytics (M/F/d)**

In Bayer Research & Early Development Oncology, we discover the next generation of cancer therapies with scientific innovation hubs in Berlin, Boston, Basel, and Oslo. Translational Sciences Oncology is a multidisciplinary department that harnesses cutting-edge technologies to enable earlier detection, precise molecular diagnosis, and personalized treatment for cancer patients. We ensure seamless translational support starting from the assessment of new targets through to preclinical and clinical studies from first-in-human through lifecycle management.

This Computational Biology Lead role is responsible to formulate and to implement computational biology strategy that enables patient-centric, data-driven insights in preclinical research, clinical trials, and/or real-world cohorts. Based on a profound understanding of the genetic and molecular heterogeneity of cancer, this role will direct data analytics that establish clear connections between drug targets and defined patient populations. This Computational Biology Lead will oversee technological innovation and scientific excellence for complex, quantitative analyses of specialized multi-omics, imaging, and/or real-world data. In particular, this role will compile and analyze internal and external high-dimensional datasets to ensure the delivery of novel targets, biomarkers, or predictive insights that may influence stage-gate decisions on the Oncology portfolio. This role will initiate, delegate, and manage innovative research projects leveraging internal and external collaborations. Through an extensive network of colleagues throughout Bayer, this role will successfully implement cross-functional solutions. This role will advance scientific leadership within the company, our network of external partners, and the broader cancer research community.

**YOUR TASKS AND RESPONSIBILITIES**
- Responsible to lead and steer a computational biology interface with a global segment of research and development, such as preclinical research, clinical trials, or real-world cohorts
- Co-create strategy with key stakeholders to derive patient-centric computational biology insights on tumor susceptibility to, or adaptations on, cancer treatment
- Coordinate and scientifically review the team’s data-driven deliverables that evaluate stage-gate decision criteria for portfolio programs
- Establish the framework for decision making, scientific best practices, and effective communication within the team
- Allocates effort among multiple direct reports to balance prioritization among delivering insights for multiple portfolio programs, while also sustaining computational biology innovation
- Pioneer computational initiatives to analyze multi-omics or imaging datasets to nominate new targets, advance new technologies, and guide tactical decisions on precision oncology therapies. Advocates for championing innovative ideas and approaches, both internally and externally
- Contributes to the prosecution of the R&D roadmap for Artificial Intelligence and Machine Learning (AI/ML) by proposing high-value business problems, contextualizing Digital Product development as a Business Owner, and identifying the added value from these approaches
- Coordinates interfaces across Research & Early Development Oncology, Oncology Biostatistics & Data Management, Data Science & AI, and IT functions

**WHO YOU ARE**
- PhD in Biological or Computational Sciences (Bioinformatics, Biostatistics, Chemistry, Computational Biology, Genetics, Molecular Biology, Statistics, or other related discipline) with very strong computational or quantitative focus
- Demonstrated experience in statistical analysis of DNA-seq, RNA-seq, single-cell, or imaging datasets in oncology with proficiency in a programming environment (such as R or Python)
- Demonstrated peer-reviewed publications in computational biology
- Ability to set, communicate, and implement a strategic vision
- Prior experience with managing direct reports
- Demonstrated critical thinking skills and learning agility, highly self-motivated, with an aspiration of continuous improvement of oneself and others
- Effective influencer, communicator, and team player with proven networking skills, both internally and externally
- Fluent in English, both written and spoken

LI-DE

**YOUR APPLICATION**

This is

  • Clinical Computational Biology Senior Leader

    Vor 5 Tagen

    Berlin, Deutschland Bayer Vollzeit

    **At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where ,Health for all, Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our...

  • Application Scientist, Computational Biology

    Vor 5 Tagen

    Berlin, Deutschland Convexity Labs Vollzeit

    **Your Role** **Responsibilities** - Collaborate with prospective clients on pilot projects using PLEX ranging from small molecule docking to genome annotation. - Identify and prioritise recently published computational biology and biology-machine learning software to onboard onto PLEX - Work closely with the Founder on improving the UX and capabilities of...

  • PhD position in Computational and Developmental Biology in Berlin

    vor 4 Wochen

    Berlin, Deutschland MDC Vollzeit

    Job Description You will develop new algorithms to infer cellular differentiation trajectories in the developing embryo from time-resolved single-cell RNA, spatial transcriptomics and lineage tracing data You will use machine learning methods to combine spatial transcriptomics data with other data modalities such as single-cell transcriptome or...

  • Computational Postdoc in Developmental

    vor 3 Wochen

    Berlin, Deutschland MDC Vollzeit

    Job Description You will develop new algorithms to infer cellular and tissue-wide differentiation trajectories from single-cell multiome (RNA + ATAC), spatial transcriptomics and lineage tracing data You will use machine learning and artificial intelligence methods to help decipher the evolutionary highly-conserved regulatory code underlying...

  • Lead C++ Engineer

    vor 2 Wochen

    Berlin, Deutschland SO Digital Recruitment Vollzeit

    One of our long standing clients, a global organisation within the Medical Industry, are on the lookout for a Lead C++ Engineer to join their Berlin Tech Hub.You will play a key role within the Hub for driving forward development, leading projects & upholding best practices within the team. Responsibilities:Working alongside the Head of the Department across...

  • Bioinformatician in Full Time

    vor 4 Wochen

    Berlin, Deutschland Leibniz-Institut für Zoo- und Wildtierforschung Vollzeit

    **Bioinformatician **in full time (100 %)** We seek a highly motivated scientist for the development and implementation of bioinformatic pipelines and statistical modelling. You will extend the work of collaborating bioinformaticians (a postdoctoral scientist appointed in the group of Sofia Forslund, Max Delbrück Center [MDC]) and integrate it with work of...

  • Scientific Staff Positions

    vor 1 Monat

    Berlin-Mitte, Deutschland Charité Vollzeit

    -Arbeitszeit **Teilzeit** Eintrittsdatum **01.01.2024** Dauer der Anstellung **Befristet** Bewerbungsfrist **15.12.2023** Einsatzort Charité **Campus Charité Mitte** Kennziffer **2542** Entgeltgruppe **E13** **Arbeiten an der Charité** **Die Stelle im Überblick** In the fields of bioinformatics: - Analysis of sequencing data from short-read...

  • Postdoctoral Researcher- Observational Learning in

    vor 4 Wochen

    Berlin, Deutschland Science of Intelligence Vollzeit

    **Reference Number: SClol-C6-59B** **Working field** **Project**:Observational learning in children and artificial agents (P59) **Project Leads**: Marcel Brass (lead PI), Verena Hafner, Julia M. Rodriguez Buritica **Description of the proposed project**: **Description of individual project**: The researcher will program a VR setup that can be interfaced...

  • Fully-funded Phd Positions in Biomedical Sciences

    Vor 5 Tagen

    Berlin, Deutschland Springer Nature Vollzeit

    **Fully-funded PhD positions in Biomedical Sciences at the MDC Berlin**: - Employer- Max Delbrück Center for Molecular Medicine (MDC)- Location- Berlin (DE)- Salary- TVöD public-sector- Closing date- 3 Mar 2024- Discipline Biomedicine, Chemistry, Computing, Life Science Job Type PhD Studentship, Researcher Employment - Hours Full time Duration ...

  • Ecological Modeller, Biostatistician in Full Time

    vor 4 Wochen

    Berlin, Deutschland Leibniz-Institut für Zoo- und Wildtierforschung Vollzeit

    **ecological modeller, biostatistician** **in full time (100 %)** We seek a highly motivated scientist for the development and implementation of statistical and mathematical modelling on the persistence and transmission of antibiotic resistance in wildlife. You will work closely with bioinformaticians (a postdoctoral scientist appointed in the group of...

  • Student Trainee Data/ai Consulting in Life Science

    Vor 5 Tagen

    Berlin, Deutschland idalab Vollzeit

    **Your start in Data/AI Consulting in Life Science & Healthcare** We are a small independent artificial intelligence consulting company for the life science and healthcare industry. We grow organically with our clients and colleagues, cultivating an open, friendly atmosphere and encouraging a colorful mix of personalities. By joining our Student Trainee...

  • Internship Opportunity: Ai4 Science

    vor 1 Monat

    Berlin, Deutschland Microsoft Vollzeit

    Over the coming decade, deep learning looks set to have a transformational impact on the natural sciences. The consequences are potentially far-reaching and could dramatically improve our ability to model and predict natural phenomena over widely varying scales of space and time. Our AI4Science team encompasses world experts in machine learning,...

  • Inceptive Apprenticeship

    vor 1 Monat

    Berlin, Deutschland Inceptive Vollzeit

    At Inceptive, we don't have titles. The title you see at the top of this page is merely our pragmatic way to make sure we reach you. Instead of topic experts working in silos, we are building an antedisciplinary team where everyone is gaining deep knowledge outside of their traditional area of expertise. For this reason, we call ourselves Beginners. Read...

  • Studentische Hilfskraft

    vor 1 Monat

    Berlin, Deutschland Zuse Institute Berlin Vollzeit

    **Zuse Institute Berlin** - **Mathematik und Informatik**: - Das Zuse Institute Berlin (ZIB) ist ein interdisziplinär arbeitendes Forschungsinstitut des Landes Berlin. Wir betreiben Forschung und Entwicklung in der anwendungsnahen Mathematik und praktischen Informatik sowie Analyse und Verarbeitung komplexer Daten in Verbindung mit...

  • Studentische Hilfskraft

    Vor 5 Tagen

    Berlin, Deutschland Zuse Institute Berlin Vollzeit

    **Zuse Institute Berlin** - **Mathematik und Informatik**: - Das Zuse Institute Berlin (ZIB) ist ein interdisziplinär arbeitendes Forschungsinstitut des Landes Berlin. Wir betreiben Forschung und Entwicklung in der anwendungsnahen Mathematik und praktischen Informatik sowie Analyse und Verarbeitung komplexer Daten in Verbindung mit...

  • Postdoctoral researcher

    vor 3 Wochen

    Berlin, Deutschland MDC Vollzeit

    Job Description Contributing to a shared grant between Manuel Irimia (CRG-UPF, Barcelona) and Nikolaus Rajewsky (BIMSB-MDC) the candidate will engage in dynamic and highly multidisciplinary collaborations with several groups in Berlin as well as with colleagues in the Irimia lab in Barcelona, Spain. Alternative splicing is a major mechanism for...

  • Inside Sales Representative

    vor 1 Woche

    Berlin, Deutschland Akoya Biosciences Vollzeit

    **About Akoya Biosciences**: As The Spatial Biology Company®, Akoya Biosciences’ mission is to bring context to the world of biology and human health through the power of spatial phenotyping. The company offers comprehensive single-cell imaging solutions that allow researchers to phenotype cells with spatial context and visualize how they organize and...

  • Territory Sales Manager

    Vor 7 Tagen

    Berlin, Deutschland Invenia Group Vollzeit

    Territory Sales ManagerHome-office based in Germany Ready to join a groundbreaking movement in genetic testing? Our client, a venture-backed healthtech startup, is leading a revolution to transform the lives of millions affected by rare genetic diseases worldwide.Backed by prominent investors and scientists, they're seeking a dedicated Territory Sales...

  • Creative Director Digital and Physical

    vor 1 Monat

    Berlin, Deutschland ART+COM AG Vollzeit

    Berlin HR-2734 Als erfahrener, konzeptstarker Creative Director zeigst du deine Exzellenz in Design und Storytelling im Spannungsfeld zwischen digitalem und physischem Raum? Souveräne Kommunikationssteuerung und strategische Beratung deiner Kunden gehören zu deinen absoluten Stärken? Wenn du gerne Neuland betrittst und mit uns die Kreation...

  • Senior C++

    vor 4 Wochen

    Berlin, Deutschland SO Digital Recruitment Vollzeit

    We have partnered up with one of the leading global companies within the Medical Industry, as they look to expand their Berlin Tech Hub, with a Senior C++ Engineer.You will play a key role within the Hub for developing, maintaining and deploying custom applications, for a pioneering name within the Medical Space.Responsibilities:Developing stable, scalable,...