Postdoctoral Researcher Position in Genomics of

vor 2 Wochen


Munich, Deutschland Klinikum der Universität München Vollzeit

Campus Großhadern
- WORKING HOURSFull time
- DEPARTMENTInstitut für Schlaganfall
- und Demenzforschung
- DEPARTMENTAG Georgakis
- DATE OF ENTRYAt the earliest possible date
- APPLICATION DEADLINESwift
- REFERENCE NUMBER2023-K-0280

The Hospital of the University of Munich, Germany, is one of the largest and most competitive university hospitals in Germany and Europe. 48 specialized hospitals, departments and institutions harbouring excellent research and education provide patient care at the highest medical level with around 11.000 employees.

Scope of duties

The project is funded by the German Research Foundation (DFG) and the Hertie Network for Clinical Neurosciences. Successful applicants will be part of an international team of investigators and will participate in the study design, data collection, data processing, and project development of a biobank of human atherosclerotic samples.

You will work on a research project with the following objectives:

- Development of polygenic risk scores for pathologies and risk factors underlying cerebrovascular disease
- Validation of the developed scores in cohorts of patients at high-risk of stroke or patients with a history of stroke
- Comparison of polygenic score predictive value to established clinical/imaging scores for cardiovascular risk prediction
- Development of integrated polygenic/clinical scores for risk prediction and testing in scenarios with clinical relevance, such as stroke survivors
- Development and testing of pharmacogenomic scores for response to standard cardiovascular risk reduction treatments and testing for clinical relevance in stroke survivors
- Coordination of GWAS and post-GWAS analyses of cerebrovascular disease phenotypes
- Mendelian randomization analyses of multiomics data with the goal to dissect novel targets of preventive strategies for stroke

Our requirements
- has a PhD degree in a relevant field (epidemiology, genetics, bioinformatics)
- has documented experience with bioinformatic analyses of omics data
- has advanced knowledge of population genetics
- is a team player with good organizational and communication skills

**Offer**:
You will be working in a multidisciplinary team with extensive expertise in stroke, epidemiology, bioinformatics, genomics, and biomarker discovery, have full access to all facilities available at the Institute for Stroke and Dementia Research, engage in national and international collaborations (e.g. ISGC) and take part in the international training programme of the Center for Stroke and Dementia Research and SyNergy.

The period of employment is two years. Starting date: June-September 2023.

Offers and services of the employer

Further education and training

Company pension scheme

Childcare services

Mobile work (if suitable)

Job ticket

Discounts

Staff accommodation

**Dr. Marios Georgakis**:
Application format

Disabled persons will be preferentially considered in case of equal qualification. Presentation costs cannot be refunded.



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