Postdoctoral Researcher

The Medical Radiation Physics Group/Professorship of the Department of Nuclear Medicine (Medical Director: Prof. Dr Ambros J. Beer) at Ulm University Hospital is looking for a- Postdoctoral Researcher (f/m/d) in Molecular Radiotherapy- The University Hospital Ulm with its employees (f/m/d) stands for modern patient care with high quality, top research and medical teaching oriented towards the future as well as training in attractive professional fields. The prerequisites for this are qualified and committed employees (f/m/d).- The position is full-time and limited to 3 years. It may be possible to continue employment after the fixed term.
- The Clinic for Nuclear Medicine provides the University Hospital Ulm and its affiliated hospitals with an entire range of services in diagnostics and therapy with radioactive drugs. The clinic has its cyclotron, radiopharmaceutical GMP laboratories, a PET/CT combination device, a PET/MR combination device, an animal PET, a SPECT/CT and three other gamma camera systems.
- Together with the University Hospital Ulm, the Clinic for Nuclear Medicine is part of the network of the Centres for Personalised Medicine (ZPM) of the four university hospitals in Baden-Württemberg and one of the top research locations in the network of the "National Centre for Tumour Diseases" with Tübingen and Stuttgart. As part of the Collaborative Research Centre 1279 on using the human peptidome for developing new antimicrobial and anti-cancer therapeutics, our focus is on molecular imaging and therapy. One goal of scientific research in "Medical Radiation Physics" is the development of targeted molecular diagnostics and treatment. One focus is on individualising molecular radiotherapy using physiologically based pharmacokinetic (PBPK) and pharmacodynamic models. Increasing integration of machine learning approaches is being sought.**Your tasks**:

- Carrying out research work on the DFG joint project with the cooperation partners at the TU Munich "Individualised radioligand therapy planning based on quantitative PET/ MR and PBPK/ PD modelling: preclinical feasibility study" (GL 236/15-1).
- Development of PBPK/PD models in MATLAB (SimBiology)
- Rigorous testing of all model components and model validation
- Development of simulation algorithms
- Error estimation of the entire modelling, fitting and simulation process
- Global sensitivity analyses
- Selection of models
- Presentation and publication of the scientific results
- Research in the field of Molecular Radiotherapy of the Chair of Medical Radiation Physics
- Participation in the guidance of doctoral and master students
- Publication of results and presentation at scientific meetings

**Our offer**:

- Payment according to TV-L and company pension scheme
- Multifaceted, responsible work in a committed, interdisciplinary team consisting of physicists, engineers, CTA/PTA/MTAs, physicians and scientists
- Diverse opportunities for further education and training; “Habilitation” is strongly supported, as is the acquisition of specialist knowledge (medical physics expert (MPE), nuclear medicine)
- Support in balancing work and family life
- Workplace health promotion

**Your profile**:

- A Master's degree or a scientific university degree completed with an equivalent qualification, preferably in the fields of medical physics, physics, medical technology, technical physics, physical engineering or in a comparable natural science or engineering discipline
- Doctorate in a relevant field
- High motivation, commitment and interest in scientific work
- Experience in modelling and simulation or the willingness and interest to familiarise oneself with the mathematical modelling of biological systems; previous medical/physical/technical knowledge and practical experience in the field of medical physics is an advantage
- Willingness to conduct interdisciplinary research in a team in medical physics, radiation biology and medicine
- Good programming skills (e.g. MATLAB)
- Good written and spoken English skills
- Contract: limited
- Level of employment: full-time-
**Are you interested?**-
**For additional information please contact**:
Recruitment is carried out by the hospital's administration in the name of and on behalf of the state of Baden-Württemberg. Severely disabled applicants (f/m/d) are given priority in case of equal suitability. Ulm University Hospital aims to increase the proportion of women in those areas in which they are underrepresented. Appropriately qualified women are encouraged to apply. Full-time positions are in principle divisible. Continued employment following a fixed-term contract is possible.