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Position: Postdoctoral Researcher

vor 3 Monaten


Heidelberg, Deutschland Springer Nature Vollzeit

**Position: Postdoctoral Researcher**:

- Employer- German Cancer Research Center in the Helmholtz Association (DKFZ)- Location- Heidelberg, Brandenburg (DE)- Salary- Competitive- Closing date- 4 Jun 2024- Discipline
Biomedicine, Life Science
Job Type
Postdoctoral
Employment - Hours
Full time
Duration
Fixed term
Qualification
PhD
Sector
Academia- You need to sign in or create an account to a job.
- Job Details
- Company

**Job Details**:
The Division of **Mechanisms Regulating Gene Expression **(headed by Prof. Dr. Michaela Frye) is seeking a

**Postdoctoral Researcher (reference number 2024-0107)**

**Job description**:
The Frye lab studies the function of RNA modifications in cancer development, metastasis and therapy resistance. You will be part of an exciting and stimulating research environment, working closely with a team of researchers, clinicians and computational analysts. Our project addresses the question how RNA modifications dynamically control transcription and mRNA translation when cancer cells are exposed to a new environment during metastasis or cancer treatment regimens for example.

We utilize a wide array of biochemical, cellular, computational and in vivo approaches to identify novel epitranscriptomic key players. A major part will be the integration of nanopore sequencing approaches for full-length transcript analyses and base modification detection.

**Requirements**:
Starting date is flexible but can be as early as June 2024.

**We offer**:

- Interesting, versatile workplace
- Excellent framework conditions: state-of-the-art equipment and opportunity for international networking at the highest level
- Remuneration according to TV-L incl. occupational pension plan for the public service and capital-forming payments
- 30 days of vacation per year
- Flexible working hours
- Possibility of mobile work and part-time work
- Family-friendly working environment, including parent-child room, counseling services, e.g. on Elder Care
- Sustainable travel to work: subsidized Germany job ticket
- Develop your full potential: access to the DKFZ International Postdoc Program and DKFZ Career Service with targeted offers for your personal development to further develop your talents
- Our Corporate Health Management Program offers a holistic approach to your well-being

**Important notice**:
**Earliest possible start date**: 01.06.2024

**Duration**:The position is initially limited to 1 year.

**Application deadline**:17.04.2024

**Contact**:
Prof. Dr. Michaela Frye
Phone +49 6221/42-4165

**Company**:
**About the German Cancer Research Center (DKFZ)**

The German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) is Germany’s largest biomedical research institute and a member of the Helmholtz Association of German Research Centers. Over 3,200 staff members from 88 nations are dedicated to performing and driving cutting edge research for a life without cancer. Organized in more than 100 divisions and research groups, the focus of our 1,400 scientists is to unravel the causes and mechanisms of cancer development and progression, and to develop novel strategies for the diagnosis, early detection, prevention and treatment of cancer though innovative translational research.

Scientists at the DKFZ have received the most prestigious academic awards, including Prof. Harald zur Hausen, awarded the Nobel Prize in Physiology or Medicine in 2008 for his pioneering work on Human Papilloma Viruses (HPV),and Prof. Stefan Hell, who received the Nobel Prize in Chemistry for his research on super-resolution imaging.

The DKFZ core site is located in Heidelberg, the “City of Science”, which is considered one of the most beautiful cities in Germany with a highly international community: An estimated 56,000 of Heidelberg’s 160,000 inhabitants have an international background - many of whom are scientists or students.

**Research Topics and Scientific Collaborations**

Research at the DKFZ is organized into six research programs:

- Cell and Tumor Biology
- Functional and Structural Genomics
- Cancer Risk Factors and Prevention
- Immunology and Cancer
- Imaging and Radiooncology
- Infection, Inflammation and Cancer

On the mission for a life without cancer, the DKFZ collaborates with renowned clinical and research institutions at the local, national and international level. A key goal is to continuously strengthen translational research activities with the aim of sustainably advancing state-of-the-art clinical cancer research in Germany and thereby improving the treatment outcomes and quality of life of cancer patients. Together with University Hospital partners across Germany, the DKFZ established the National Centers for Tumor Diseases (NCT) as leading Comprehensive Cancer Centers in Germany, as well as the Hopp Childrens’ Tumor Center (KiTZ) in Heidelberg with a specific focus on pediatric oncology. Within the German Cancer Consortium for Translational Cancer Research (DKTK), researc