(Senior) Postdoc

**Our mission as research center**: Discover personalized medical solutions for environmentally triggered diseases to promote a healthier society in a rapidly changing world.

The (HPC) founded and funded by Helmholtz Munich stands for the intelligent fusion of biomedical sciences, engineering and digitization. At HPC, top scientific talents from across the globe work together on the development of novel solutions that make a difference in the prevention, diagnosis and treatment of diseases.

The investigates the molecular mechanisms of ageing using single-cell genomics with the aim to discover novel molecular makers of ageing and advance the development of anti-ageing therapeutic approaches. In particular, we focus on the common molecular mechanisms between ageing and chronic liver diseases, and we develop novel methodologies to study the impact of age-related cellular heterogeneity in the development and progression of chronic diseases.

We are looking for a highly motivated

(Senior) Postdoc - Molecular Ageing (f/m/x) 102065

Full time

Neuherberg near Munich

Postdocs

**Responsibilities**:

- Design and perform genomic experiments involving dissociating and isolating cells and nuclei from tissue samples for single cell multiomics and other molecular biology techniques.
- Design and perform wide range of imaging-based experiments, including immunofluorescence, immunohistochemistry, RNAscope and Basescope.
- Dissection of mice to routinely maintain on-going collection of multiple tissue samples for bioarchiving and collaborative work.
- Support cell culture experiments, particularly organoid differentiation, functional tests and in vitro phenotyping experiments.
- Perform image acquisition using con-focal microscopy, and analysis using Zeiss and ImageJ softwares.
- Diligently maintain databases containing tissue samples, histology records, and protocol.
- Write reports and research manuscripts, as well as grant proposals, and participate in conferences to present your own work.
- Work and collaborate with colleagues from other fields of scientific disciplines,
- Supervise student projects at BSc, MSc, and PhD level.

Your qualifications
- Hold a PhD in the field of life science, biology, molecular biology, medicine or similar.
- Excellent publication record (including at least one first author, peer-reviewed research paper).
- Extensive experience in cell culture and animal handling.
- Experience in the tissue dissociation and genomic sequencing protocols.
- Experience in histopathological techniques.
- Strong organisational skills, self-driven to work independently, and with a positive and collaborative attitude to engage with biomedical and computational scientist, and clinical colleagues.
- Fluent in written and spoken English.

What we offer you

work-life balance flexible working hours & working-time models continuous education and training 30 days annual leave
on-site health management service
home office options on-site nursery & holiday care elder care company pension scheme discounted public transport ticket Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and world-leading research institutions it offers an intellectually stimulating environment.

Provided that the prerequisites are fulfilled, a salary level up to E 13 is possible. Social benefits are based on the collective agreement for the federal public service (TVöD). The position is (initially) limited to two years, under certain circumstances an extension can be arranged.

If you have obtained a university degree abroad, we require further documents from you regarding the recognition of the degree.

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Helmholtz Pioneer Campus
Ingolstädter Landstraße 1

85764 Neuherberg near Munich