Academic Staff in The Research Project “metabolic
vor 2 Monaten
Furtwangen University (HFU) is an innovative, constantly evolving institution, located and rooted in Germany’s Black Forest region and with a strong international orientation. Our focus areas are computer sciences, technology, business, media and health sciences. Among the universities of applied sciences in Baden Württemberg we are one of the strongest research universities and have more than 5.000 students, over 450 employees and more than 190 professorships across our three campuses in Furtwangen, Villingen-Schwenningen and Tuttlingen as well as the research centre in Rottweil and the study centre in Freiburg.
Furtwangen University is offering a position to the earliest possible date in the Medical & Life Sciences department as
**“Academic Staff” (male / female / non-binary)**
**in the research project “Metabolic Distinction of Apoptosis-Induced Compensatory Proliferation and Apoptosis-Induced Apoptosis”, MetaLife, founded by the German Research Foundation (DFG)**
**Your tasks will include**: The position is part of a DFG-funded project that focuses on the identification of metabolic signalling molecules released by dying cells. The project builds on recent findings that apoptotic cells secrete anti-inflammatory metabolites that promote wound healing (see e.g. here DOI: 10.1038/s41586-020-2121-3).
The new project focuses on the question of which biologically active metabolites are secreted during different forms of cell death (e.g. apoptosis or necroptosis) and what effects these have on other cells. An activity-based approach will be employed to identify secretomes that induce an equal or opposite effect in the target cells and subsequently identify the responsible metabolites using high-resolution ion mobility coupled mass spectrometry. For this purpose, state-of-the-art methods such as cell cultivation and cell-cell signalling in microfluidic systems, multiparameter flow cytometry and ion mobility coupled mass spectrometry are used.
Experience in flow cytometry, microfluidics, liquid chromatography (e.g. HPLC, UHPLC), extraction methods for metabolites from biological samples, bioinformatic tools such as R or Phyton, mass spectrometry or statistical analysis of metabolomics datasets is an advantage. Good written and spoken English and German language skills are also expected.
**We are offering**: You will find this a stimulating position with diverse tasks, working as part of a motivated and open team and enjoying the numerous benefits offered by a position within the German civil service system.Kennziffer 2024-080-MLS-D
- wöchentliche Arbeitszeit 25,675 Stunden
- Eingruppierung Entgeltgruppe 13 TV-L
- Dienstort Campus Villingen-Schwenningen
Ansprechperson
**Prof. Dr. Hans-Peter Deigner**
- Telefon: +49.7720/307-4232
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