Research Associate/ Phd Student
vor 1 Woche
**Vacancy ID 11847**:
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TUD Dresden University of Technology, as a University of Excellence, is one of the leading and most dynamic research institutions in the country. Founded in 1828, today it is a globally oriented, regionally anchored top university as it focuses on the grand challenges of the 21st century. It develops innovative solutions for the world's most pressing issues. In research and academic programs, the university unites the natural and engineering sciences with the humanities, social sciences and medicine. This wide range of disciplines is a special feature, facilitating interdisciplinarity and transfer of science to society. As a modern employer, it offers attractive working conditions to all employees in teaching, research, technology and administration. The goal is to promote and develop their individual abilities while empowering everyone to reach their full potential. TUD embodies a university culture that is characterized by cosmopolitanism, mutual appreciation, thriving innovation and active participation. For TUD diversity is an essential feature and a quality criterion of an excellent university. Accordingly, we welcome all applicants who would like to commit themselves, their achievements and productivity to the success of the whole institution.
At the **Center for Molecular and Cellular Bioengineering** (**CMCB**), **Biotechnology Center (BIOTEC)**, the **Research** **Group OncoMechanics** offers a position as
**Research Associate/ PhD Student** (M/F/x)
(salary in accordance with the MSCA-DN regulations (if necessary, additional payment of a family allowance if relevant personal circumstances exist)
starting on** April 1, 2025**. The position is limited to three years, with the option of extension. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz - WissZeitVG). The position aims at obtaining further academic qualification (usually PhD).. The position is in the framework of a European MSCA-Doctoral Network (DN) program (GA: 101168976) entitled “Autonomous Scanning Probe Microscopy for Life Sciences and Medicine powered by Artificial Intelligence (SPM4.0)” that involves research centers/academic institutions and three companies from Spain, Sweden, France, Germany, Italy, Poland, Czech Republic, and UK.
The SPM4.0 partner hosting the PhD student is the Research Group OncoMechanics led by Dr Anna Taubenberger at the CMCB. The Research Group OncoMechanics focuses on mechanical phenotyping of cells and tissues and aims to obtain a better understanding of how mechanical forces and interactions within the tumour microenvironment influence cancer progression and treatment responses. The group's interdisciplinary approach combines concepts from biomechanics, cancer biology, and materials science to study cellular responses to mechanical stimuli and state-of-the art biophysical tools. They aim to develop innovative therapeutic strategies by leveraging insights into the mechanical behaviour of tumour tissues and their implications on cancer dynamics.
**Tasks**:
- participate in research activities of the Research Group OncoMechanics within the above-mentioned SPM4.0 project
- biophysical characterization of mechanical properties of established cell lines and patient-derived samples at the nanoscale using scanning probe microscopy (atomic force microscopy, AFM) and complex data and image analysis
- to integrate and validate newly developed algorithms for autonomous scanning and data analysis
- establishment of in vitro cell cultures and morphological cell characterization using advanced fluorescence microscopy
- writing of scientific manuscripts for publication and data presentations at conferences and project meetings
- lab rotations and scientific exchange with partner labs of the SPM4.0 network
**Requirements**:
- university degree (Diploma/Masters) in biophysics, biotechnology, (bio)physics or biology; you must not have a PhD degree at the date of recruitment.
- fulfil the requirements to be enrolled in a PhD program (e.g. DIGS-ILS)
- You must comply with the mobility rules of to the MSCA-DN regulations: not have resided or carried out your main activity (work, studies, etc.) in Germany for more than 12 months in the 36 months immediately before recruitment data.
- ability to maintain accurate and up to date records
- understanding of the research process
- ability to organise and prioritise own work and organize research within the project timetable
- problem-solving skills
- computer literacy
- wet lab skills (molecular biological assays, cell culture, microscopy)
- strong interest in working in an interdisciplinary team at the interface of physics, biomedical engineering and biology
- good communications skills in English
- very high motivation and effective team working
**We offer**:
- 3-year full-time employment contract.
- enrolment in an international PhD program
- exposure to a multidiscipl
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