Doctoral Researcher

Vor 4 Tagen


Stuttgart, Deutschland Dr. Margarete Fischer-Bosch Institut für Klinische Pharmakologie Vollzeit

**Company Description**
The Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart (Director Prof. Dr. M. Schwab) is operated by the Robert Bosch Foundation. Since its foundation in 1973, the institute has emerged as Germany's largest and most renowned research unit in the field of clinical pharmacology. Main research activities concentrate on the influence of genetic and non-genetic factors on the variability of drug efficacy and their contributions to disease development.

**Research areas**:Tumor biology, copy number alterations, gene expression profiling, signaling pathway analysis, multiplex protein stainings, _in vitro_ and _ex vivo_ tumor models, tumor therapy

This project is part of a research group that seeks to identify new therapy options for lymphoma and patients by bringing together refined molecular biological characterization of tumors and pre-clinical testing of innovative novel drugs.

The main topics of the project are:

- Molecular characterization of patient tumors towards the identification of suitable novel therapy targets
- Development of 3D lymphoma models
- Pre-clinical efficacy and mechanism of action of promising novel drugs

**Qualifications**
- Strong interest in tumor biology and therapy
- Experimental background in molecular biology is preferred
- Experience in OncoScan analysis, Nanostring-based RNA expression measurements, western blot analysis, FACS and/or cell culture (human cells) is a plus

**Additional Information** Our offer**:
We offer ideal conditions for you to complete your doctoral degree:

- The Research Group PharmacoOmics & Lymphoma is embedded in the scientific environment of the Bosch Health Campus providing state-of-the-art research facilities and a highly integrative network of life science groups
- The position is for a fixed term of three years. Salary will be in line with 65% of pay group 13 of the Collective Agreement for the Public Service (TVöD).

The anticipated start date is March 1st, 2025.

**Contact**:
**Dr. Heike Horn**

A diverse and inclusive working environment with equal opportunities, in which everyone can realize their potential, is important to us.

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