Phd Position in Translational Cancer Immunology

vor 3 Monaten

München, Deutschland Klinikum der Universität München Vollzeit

München, Campus Großhadern- WORKING HOURS- Part time- INSTITUTION- Medizinische Klinik III (Onkologie)- DEPARTMENT- Subklewe lab- DATE OF ENTRY- 01.11.2024- APPLICATION DEADLINE- 31.10.2024- REFERENCE NUMBER- 2024-K-0508The Hospital of the University of Munich, Germany, is one of the largest and most competitive university hospitals in Germany and Europe. 48 specialized hospitals, departments and institutions harbouring excellent research and education provide patient care at the highest medical level with around 11.000 employees.

Scope of duties
- Antigen Profiling of primary acute myeloid leukemia (AML) cells using single-cell RNA sequencing and multiparameter flow cytometry
- Evaluation of novel T-cell bispecific antibody constructs for treatment of AML
- Dissecting resistance mechanisms in hematologic malignancies towards bispecific antibodies and CAR-T cell therapies
- Daily Research Methods:

- Aseptic cell culture of cell lines and primary patient material
- Isolation of peripheral blood and bone marrow mononuclear cells from patients and healthy donors
- Cytotoxicity assays, co-cultures, immune cell activation and inhibition assays, proliferation analysis, and cytokine screening
- Advanced flow cytometry
- Presenting research findings at national and international conferences

Our requirements
- ** Educational Background**: M.Sc. in life sciences, biology, biochemistry, molecular biology, or related disciplines.
- ** Passion for Impact**: Eager to contribute to clinically oriented research that impacts patient care and treatment outcomes.
- ** Driven and Committed**:Highly motivated with a dedicated approach to research, demonstrating the ability to work independently and efficiently.
- ** Team Player**: Collaborative and team-minded, thriving in a multidisciplinary research environment.
- ** Specialized Knowledge**: A strong theoretical background in immunology is a plus, and knowledge in biostatistics will be advantageous.
- ** Technical Expertise**: Experience in flow cytometry and handling primary patient material is an asset.

**Offer**:

- Join our excellent team, dedicated to clinically oriented research in the field of immunotherapy.
- Remuneration is based on the Collective Agreement for the Public Sector of the Länder (TV-L) including all allowances customary in the public sector.

Offers and services of the employer

Further education and training

Job ticket

Company pension scheme

Discounts

Childcare services

Staff accommodation (if available)

Mobile work (if suitable)

**Frau Prof. Dr. Subklewe, Marion**:
+49 89 4400 73133

Application format

Disabled persons will be preferentially considered in case of equal qualification. Presentation costs cannot be refunded.

Please note that we cannot reimburse travel expenses incurred through interviews.

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