De-working Student/ Dissertation Evidence Generation

vor 2 Monaten

Munich, Deutschland Daiichi Sankyo Europe Vollzeit

**Passion for Innovation. Compassion for Patients.**:
With over 120 years of experience and more than 17,000 employees in over 20 countries, Daiichi Sankyo is dedicated to discovering, developing, and delivering new standards of care that enrich the quality of life around the world.

In Europe, we focus on two areas: The goal of our Specialty Business is to protect people from cardiovascular disease, the leading cause of death in Europe, and help patients who suffer from it to enjoy every precious moment of life. In Oncology, we strive to become a global pharma innovator with competitive advantage, creating novel therapies for people with cancer.

Our European headquarters are in Munich, Germany, and we have affiliates in 13 European countries and Canada.

**Working Student (M/F/x) / Master’s Thesis**:
**Mission**:
We are offering a working student/ thesis position (M/F/x) for an interesting project. The EQ-5D-5L questionnaire evaluates health status across five dimensions, allowing respondents to indicate their level of functioning or discomfort. National value sets assign numerical values to these states, crucial for costutility models. This thesis aims to explore alternative methods for estimating health-state utility (HSU) in oncology, involving literature review and comparison of statistical methods using clinical trial data.

**Tasks and responsibilities**:

- Supporting our team in the field of health economics
- Assessment of health conditions and their impact on quality of life
- Utilization of the EQ-5D-5L questionnaire in clinical trials and economic evaluations
- Evaluation of health status across five dimensions: Mobility, Self-care, Usual activities, Pain/Discomfort, Anxiety/Depression
- Derivation of a health state profile as a 5-digit number from 11111 (no problems) to 55555 (extreme problems)
- Utilization of national value sets to assign numerical values reflecting population preferences
- Exploration of alternative approaches to estimating HRQoL by disease status
- Conducting a literature review to identify meaningful analysis strategies
- Comparison of different statistical methods using clinical trial data, with the possibility of statistical simulation

**Personal skills and professional experience**:

- Good programming skills in R and/or SAS
- Good knowledge of event-history analysis, longitudinal modelling. Knowledge of causality methods is a plus
- Excellent oral and written communication skills
- Good command of English
- Self-starter, independent thinker
- We will provide laptop for working
- The student will be expected to make presentations from time to time to internal stakeholders
- Eligible to work for us in the UK

**Why work with us?**:

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