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Scientific Researcher

vor 4 Monaten


BerlinWedding, Deutschland Charité Vollzeit

-Arbeitszeit

**Teilzeit**
Dauer der Anstellung

**Befristet**
Bewerbungsfrist

**22.12.2023**
Einsatzort Charité

**Campus Virchow-Klinikum, Wedding**
Kennziffer

**2444**
Entgeltgruppe

**E13**

**Working at the Charité**

The aim of our group is to dissect how tumor and immune cells interact and to develop strategies to achieve long-term tumor control using therapeutic immunomodulation based on modern single cell genomics sequencing methods and primary human blood or bone marrow samples.
Our approach entails deep analyses of our own and public immunogenomic single cell and bulk datasets, followed by in-vitro validation experiments.

**Job Overview**
- Collection, cryoconservation and processing of primary human blood and bone marrow samples
- Planning and executiong of single cell and bulk sequencing experiments
- Analysis of single cell datasets (single cell RNA / DNA / TCR / ATAC sequencing)
- Analysis of immunogenomics datasets (i.e., T cell and B cell receptor sequencing; whole-exome sequencing, etc.)
- Development of custom sequencing methods and analysis pipelines
- Management and processing of raw data on cluster infrastructure
- Planning and execution of follow-up experiments in collaboration with other members of the group (for example co-culture experiments with T cells and tumor cells; reexpression of TCR; etc.)

The PhD project will be embedded in the work of the Max-Eder research group led by Livius Penter which aims to answer
translational tumor immunologic questions in the context of blood malignancies using cutting-edge immunogenomics data
analysis. A focus of the work will be data analysis using custom analysis solutions.

We aim to work in an international and collaborative environment together with partners in the Berlin area, for example at
the Berlin Institute of Health (BIH) or Berlin Institute for Medical System's Biology (BIMSB) on relevant projects with high impact.
We put an emphasis on the individual career development of all our team members.
Scientific staff is given sufficient time to carry out their own scientific work in accordance with their employment relationship.

**We are looking for**
- Completed degree in biological sciences, biotechnology, bioinformatics, or a related field
- Previous experience in the above mentioned methods
- Programming skills in R, Python, shell, or similar languages in a UNIX environment
- Knowledge of Word, Excel, and PowerPoint
- Interest in learning and developing novel sequencing and bioinformatics analysis methods
- Critical and independent working style
- Interest in immunological and tumorgenetic questions, as well as a combination of wet and dry lab work
- Interest in collaborating with national and international research groups
- Excellent proficiency in both written and spoken English
- Strong organizational skills

**Advantages at the Charité**
- A relaxed but highly professional collaboration in a familiar, motivated, interdisciplinary team
- A future-oriented, varied and challenging job with a high degree of personal responsibility and personal freedom of action
- Extensive free continuing education and training opportunities up to and including university studies
- Discounts on many employee offers for shopping, travel, sports
- Our company pension scheme provides our employees with additional security in old age

**Job Information**
- Pay scale E13 according to TVöD- VKA- K. The grouping takes place under consideration of the qualification, the respective experience level is calculated from the completed professional years. The annual salary (gross) is given for a full-time position without annual bonus, allowances and additional services. You can find the collective agreement here.
- The working time is part-time with 25,35 hours per week
- At our company 30 days of vacation are standard
- Reference number: DM.208.23b

**Ihre Bewerbung**:
Dr. med. Livius Penter

+49-(0)30-450-553 615

**Vorteile und Leistungen**:
**Faire Löhne und Arbeitskonditionen**:

- An der Charité erwarten dich Tarifverträge mit fairem Gehalt, vielfältigen Zusatzleistungen und 30 Tagen Urlaub.**Interdisziplinäres Arbeiten**:

- Wir kooperieren mit anderen Kliniken weltweit und arbeiten auch im Alltag interdisziplinär zusammen. Unsere Arbeit ist geprägt von einem kontinuierlichen Austausch untereinander.**Stimulierendes Arbeitsumfeld**:

- An der Charité triffst du auf herausragende Kolleginnen und Kollegen. Ein optimales Umfeld für die eigene Weiterentwicklung.