Platform Leader

vor 1 Monat

Heidelberg, Deutschland Springer Nature Vollzeit

**Platform Leader - Genome editing in preclinical disease models**:

- Employer- Medizinische Fakultät Heidelberg der Universität Heidelberg- Location- Heidelberg, Baden-Württemberg (DE)- Salary- Closing date- 9 Apr 2024- Discipline
Applied Science, Health Science, Life Science
Job Type
Postdoctoral, Project Manager, Researcher
Employment - Hours
Full time
Duration
Fixed term
Qualification
PhD
Sector
Academia- You need to sign in or create an account to a job.

**Job vacancy**

The Heidelberg Medical Faculty of the University of Excellence Heidelberg is established nationally and internationally as an outstanding location for innovative research. The scientific institutes and clinics on the Heidelberg campus combine experience in practice-oriented and interdisciplinary training and teaching with modern research at the highest level. The Faculty of Medicine is embedded in the Health + Life Science Alliance Heidelberg Mannheim. This alliance, backed by seven leading research institutions, aims to transform the Rhein-Neckar region into an internationally leading biomedical technology hub, with a focus on life sciences, health economics, and medical technology. This will be achieved through collaborative efforts in utilizing and advancing high-tech platforms. The interinstitutional research and development network includes Heidelberg University, Heidelberg University Hospital (UKHD), Mannheim University Hospital (UMM), the German Cancer Research Center (DKFZ), the European Molecular Biology Laboratory (EMBL), the Max Planck Institute for Medical Research (MPImR), and the Central Institute of Mental Health (ZI). To support technology advancement, the Heidelberg Faculty of Medicine at Heidelberg University seeks a

**Platform Leader (m/w/d)**

**Genome editing in preclinical disease models**

Full-time (100 %), Initially limited until December 31, 2027.

**The research and tasks of the platform include**:

- Development and optimization of genome editing procedures: The group works on developing new technologies and methods for precise genome editing and further advancing existing procedures. This includes techniques such as CRISPR/Cas9, Base Editing, and Prime Editing.
- Development of in vitro models: The Junior Research Group also utilizes in vitro models derived from iPS cells. These cell models enable the investigation of disease mechanisms in a controlled environment and the testing of potential therapeutic approaches.

**Your responsibilities as the head of the Platform**:

- You are responsible for further development of technologies in the field of genome engineering.
- You will help establish and lead the platform as an information, contact, and service facility for members of the Health + Life Science Alliance.
- In your role as the platform leader, you will be responsible for finances and personnel.
- In close coordination with the Department of General Pharmacology and in collaboration with Health + Life Science Alliance management your role will involve spearheading the further development of the platform.
- You will actively be involved in research questions related to genome editing within the Health + Life Science Alliance Heidelberg Mannheim.
- You will establish collaborative projects with other members of the Health + Life Science Alliance within the framework of funding instruments for research consortia (DZGs, CRCs) at Heidelberg University.
- Your expertise will be integrated into future project proposals to acquire further funding for the implementation of genome engineering techniques.
- Optionally, you may participate in university self-administration and teaching.

**Your profile**:

- A successfully completed Ph.D. in biosciences, medicine, veterinary medicine, pharmacy, or an equivalent degree is required.
- Good English language skills and German language skills are desirable.
- You demonstrate the ability to work independently and autonomously.
- Evidence of leadership experience and experience in supervising final theses is advantageous and will be positively evaluated.
- Enthusiasm for an exciting, dynamic, and challenging position in medically oriented basic research, as well as openness and willingness to collaborate in scientific standardization communities.

**What we offer**:

- Close collaboration and support in administrative tasks with the Department of General Pharmacology (Head Prof. Dr. Marc Freichel) and other research groups within the Health + Life Science Alliance interested in genome editing techniques.
- A diverse field of activity at the interface of medicine, biology and bioinformatics.
- The opportunity to be closely involved in the activities and networks of Heidelberg University and the Health + Life Science Alliance.
- In addition you will benefit from the extensive research network of the involved workgroups and collaboration partners.
- Modern facilities and laboratory equipment at the Pharmacological Institute.
- Regular training and further

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