Postdoc in Computational Neurobiology

vor 5 Monaten

Munich, Deutschland Helmholtz Zentrum München Vollzeit

102403

Full time
39 h/week

Neuherberg near Munich

Home Office Options

We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health.

Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. We particularly excel in the fields of basic research, bioengineering, artificial intelligence, and technological development.

Through this research, we build the foundations for medical innovation. Together with our partners, we seek to accelerate the transfer of our research, so that laboratory ideas can reach society and improve people’s quality of life at the fastest rate possible.

This is what drives us. Why not join us and make a difference?

The Computational Health Center (CHC) is globally recognized for innovations in data analysis and modeling of biological systems and diseases, anchored at Helmholtz Munich and the Technical University Munich.

The Research Team Computational Neurobiology is participating in several NIH-funded initiatives, including the Accelerating Medicines Partnership for Alzheimer's Disease, and is pioneering integrative metabolomics and multi-omics research in neuropsychiatric and neurodegenerative disorders. The position is part of NIH’s Translational Bioinformatics for Drug Repositioning and Combination Therapy program and funded through a collaborative project with Jan Krumsiek's lab (Weill Cornell Medicine, NYC, USA).

Prof. Matthias Tschöp (Dr. Med., Dr. hc.), CEO of Helmholtz Munich: "We believe that excellent research requires a range of different perspectives. Diverse teams reach better solutions and are more innovative in their research topics.

Establishing our Diversity Management Strategy demonstrates our commitment to ensuring an appreciative company culture based on mutual respect. We are also implementing diversity-sensitive processes throughout our whole organization."

Your tasks
- Collecting, processing, and harmonizing large-scale omics-based (association) data and integration into the AD Atlas Neo4j database.
- Further development and extension of the online user interface at, including tools for computational drug repositioning and suitable visualization of results thereof.
- Identification of disease-relevant genes using graph-, machine/deep learning-, and integrative omics-based approaches to be utilized as seeds for network-based in silico drug repositioning.
- Conducting multi-omics analyses of drug signatures: transcriptome, proteome and particularly metabolome.
- Conceptualizing and implementing unified scoring schemas for weighting edges (intra-/inter-omic and trait associations) integrated from heterogeneous sources.

Access to several international research consortia consisting of a team of experts across disciplines will provide you with many opportunities to expand your network, learn from colleagues, and disseminate your own research at international conferences. Our team in Munich is passionate, dynamic, international and very supportive. We look forward to getting to know you

**Profile**:

- A PhD in computational biology, biostatistics, computer science, neuroscience, or a related field.
- Strong programming and data visualization skills (R and Python).
- Experience in working with large-scale omics data (preprocessing, QC, annotation).
- Knowledge of statistics in the context of biomedical research (especially association analyses with molecular data/biomarkers).
- Excellent communication and presentation skills, including experience in communicating across discipline boundaries.
- Enthusiasm and a high level of motivation for scientific work and reproducible research.

Desirable qualifications
- Experience in using the Neo4j graph database management system and in developing R Shiny apps is an advantage.
- Background and strong interest in neuropsychiatric/neurodegenerative diseases (particularly Alzheimer's).

**Benefits**:
Since 2005, we hold the TOTAL E-QUALITY award for exemplary action in the sense of an equal-opportunity organizational culture.

Helmholtz Munich is actively committed to diversity and inclusion in practice and is sustainably committed to equality.

The Diversity Charter has set itself the goal of promoting diversity in the world of work. By signing the charter, we commit ourselves to create an appreciative working environment for all employees.

If you fulfil all the requirements, you may be eligible for a salary grade of up to E 13. Social benefits are based on the Collective Wage Agreement for Public-Sector Employees (TVöD). This position is for a fixed term until until 31.5.2026.

If you have obtained a university degree abroad, we will require further documents from you regarding the comparability of your degree.

Interested in applying?

We are Helmholtz Munich.

Why join us?

Helmholtz Munich
Deutsches Forschungszentrum für Ges

  • PostDoc in computational biomedical imaging

    vor 6 Monaten

    Munich, Deutschland Technical University of Munich Vollzeit

    PostDoc in computational biomedical imaging (f/m/d) Chair of Biological Imaging 14.02., Wissenschaftliches Personal The Chair of Biological Imaging ( CBI ) at the Technical University of Munich ( TUM ) and the Institute of Biological and Medical Imaging (IBMI) at Helmholtz Munich are an integrated, multi-disciplinary research unit, which...

  • Postdoc and Ph.d. Student in Biology with

    vor 6 Monaten

    Munich, Deutschland Technische Universität München Vollzeit

    **To strengthen our team, we are recruiting a highly motivated PostDoc and Ph.D. student in biology with computational background** **Profile**: - We are looking for a variety of academic backgrounds: molecular biology, biomedical research, bioinformatics - You hold a Ph.D. in molecular biology and have a computational background (applies for the PostDoc...

  • Postdoc in Computational Biomedical Imaging

    vor 5 Monaten

    Munich, Deutschland Helmholtz Zentrum München Vollzeit

    102265 Full time Neuherberg near Munich We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. We...

  • Research Scientist Computational Modeling

    vor 5 Monaten

    Munich, Deutschland Deutsches Herzzentrum München des Freistaates Bayern Vollzeit

    The** German Heart Center** **Munich** of the Free State of Bavaria, affiliated to the** Technical University of Munich,** is a clinic with international reputation and state-of-the-art technical and medical equipment. The **Department of Pediatric Cardiology** is seeking a **Research Scientist Computational Modeling (m/**f/**d)**: The project ‘Digitaler...

  • Postdoctoral Fellowship

    vor 6 Monaten

    Munich, Deutschland Klinikum rechts der Isar der Technischen Universität München Vollzeit

    **Hospital rechts der Isar (MRI) of Munich Technical University (TUM)** **Postdoctoral Fellowship (M/F/d) - Biophysics** **Full-time | temporary contract | **Klinik und Poliklinik Med I. (Cardiology Department)** **Your responsibilities**: - Assisting under-/graduate students in research and publications related to the project - Management of...

  • Postdoc - Mechanisms to Control Alternative

    vor 6 Monaten

    Munich, Deutschland Helmholtz Zentrum München Vollzeit

    : Discover personalized medical solutions for environmentally triggered diseases to promote a healthier society in a rapidly changing world. The UNLEASH Synergy project, which is jointly funded by the European Research Council (ERC) and UK Research and Innovation (UKRI), is a 6-year international collaborative programme that will study mechanisms...

  • Postdoc in Neuroscience

    vor 6 Monaten

    Munich, Deutschland Helmholtz Zentrum München Vollzeit

    102356 Full time 39 hrs./week Neuherberg near Munich We are Helmholtz Munich. We discover breakthrough solutions for better health in a rapidly changing world. We improve people's quality of life through excellent research. Why not join us and make a difference? The (HPC) founded and funded by Helmholtz Munich stands for the intelligent fusion of...

  • Postdoc in Epigenetics

    vor 5 Monaten

    Munich, Deutschland Helmholtz Zentrum München Vollzeit

    102417 Full time 39 hrs./week Neuherberg near Munich Home Office Options We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and...

  • Postdoc/ Scientist

    vor 6 Monaten

    Munich, Deutschland Helmholtz Zentrum München Vollzeit

    102393 Full time 39 h/Woche Munich Home Office Options We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational...

  • HiWi Position in Bioinformatics

    vor 6 Monaten

    Munich, Deutschland Technical University of Munich Vollzeit

    scRNA-Seq in Immunology, flexible HiWi position with home office opportunity HiWi Position in Bioinformatics - scRNA-seq in Immunology 21.05., Studentische Hilfskräfte, Praktikantenstellen, Studienarbeiten Decoding the human immune system on the single-cell level Our research group employs state-of-the-art single cell sequencing...

  • Biomedical Imaging Research Fellow

    vor 2 Wochen

    Munich, Bayern, Deutschland Technical University of Munich Vollzeit

    PostDoc in computational biomedical imagingThe Opportunity:We are an integrated, multi-disciplinary research unit providing bioengineering solutions to urgent societal needs at the Technical University of Munich and Helmholtz Munich.Catalyzing breakthroughs in biology, medicine, and the environment, our scientists develop next-generation imaging and sensing...

  • Postdoc (F/m/x) - Repetitive Elements in The

    vor 6 Monaten

    Munich, Deutschland Helmholtz Zentrum München Vollzeit

    102325 Full time 39 hrs./week Munich We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. We...

  • Postdoctoral Researcher for Data Analysis and Machine Learning of Multimodal Biomedical Data

    vor 1 Monat

    Munich, Deutschland LMU Klinikum Vollzeit

    Scope of duties We are looking for a postdoc to join the growing team of the machine learning and data analysis group at the Institute for Stroke and Dementia Research (ISD).  Our group uses computational analysis and machine learning algorithms to identify patterns and relationships from complex, multimodal, and multiscale datasets of the brain in...

  • Postdoc (F/m/x) - Molecular Determinants of Genome

    vor 6 Monaten

    Munich, Deutschland Helmholtz Zentrum München Vollzeit

    102372 Full time 39 hrs./week Munich We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. We...

  • Senior scientific software developer for AI in regulatory genomics

    vor 6 Monaten

    Munich, Deutschland Technical University of Munich Vollzeit

    Senior scientific software developer for AI in regulatory genomics 18.03., Wissenschaftliches Personal About us The Chair of Computational Molecular Medicine, led by Prof Julien Gagneur, develops computational approaches to study the genetic basis of gene regulation and its implication in diseases. Applications of our work range from...

  • Postdoc in Machine Learning for Health

    vor 5 Monaten

    Munich, Deutschland Helmholtz Zentrum München Vollzeit

    102396 Full time Neuherberg near Munich Home Office Options We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and...

  • Postdoc - Institute of Ai for Health (F/m/x)

    vor 6 Monaten

    Munich, Deutschland Helmholtz Zentrum München Vollzeit

    102310 Full time Neuherberg near Munich Home Office Options We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and...

  • Postdoc - Department Signaling and Translation

    vor 5 Monaten

    Munich, Deutschland Helmholtz Zentrum München Vollzeit

    102333 Full time Neuherberg near Munich We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. We...

  • Postdoc - Mechanisms of Beta Cell Identity and

    vor 6 Monaten

    Munich, Deutschland Helmholtz Zentrum München Vollzeit

    102392 Full time Neuherberg near Munich Home Office Options We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and...