Postdoc (F/m/d) - Protein Homeostasis in Mammalian

vor 4 Monaten


Köln, Deutschland Universität zu Köln Vollzeit

We are one of the largest and oldest universities in Europe and one of the most important employers in our region.
make us attractive for students and researchers from around the world. We offer a wide range of career opportunities in
science, technology, and administration.

The ProteOOstasis Lab is a recently established research group at

CECAD, located on one of Europe‘s top research campuses with state
- of-the-art facilities. We focus on protein homeostasis in mammalian

oocytes and its demise during reproductive aging. We are looking for an

enthusiastic postdoc with a background in proteostasis, lysosomal sig
- nalling, and/or protein biochemistry. We offer a diverse range of research

projects at the intersection between biochemistry, cell, and molecular

biology, and an interdisciplinary range of experimental systems, from in

propose additional projects within the scope and expertise of the lab.

YOUR TASKS
- Dissect the regulation of endolysosomal super-organelles in mouse

oocytes and its demise during reproductive aging
- Perform isolation, microinjection, immunostaining and imaging of

mouse oocytes and embryos
- Optimise ultra-low-input proteomics and lipidomics for mouse

oocytes
- Develop your own research project under the project in autonomy

under the supervision of the PI
- Supervise undergraduate students and share your knowledge and

expertise
- Promote a culture of respect, collaboration and mutual support in

the lab

YOUR PROFILE
- You hold a PhD in Biology, Biochemistry or similar field
- You have a proven record of research excellence, such as such as

being a co
- or first author of a publication (co-)first-author paper
- You are a team player who thrives in a collaborative working en
- vironment
- You have excellent written and oral English skills
- You are willing to work with mice. Previous accreditation as animal

experimenter is desirable but not required
- You have a background in proteostasis, endolysosomal trafficking/

signalling, biomolecular condensates and/or protein biochemistry
- Previous experience with oocyte/embryo manipulation, imaging,

image analysis, and/or in vitro reconstituted systems is an advantage

WE OFFER
- A large, international, top European research campus with state-of
- the-art facilities
- An enthusiastic, collaborative, and curiosity-driven research en
- vironment
- A diverse working environment with equal opportunities
- Support in balancing work and family life
- Extensive advanced training opportunities
- Occupational health management offers
- Flexible working time models
- Opportunity to work remotely

The University of Cologne promotes equal opportunities and diversity.

Women will be considered preferentially in accordance with the Equal

Opportunities Act of North Rhine-Westphalia (Landesgleichstellungs

social origin, religion, disability, age, sexual orientation and identity.

The position is available from 1 January 2025 on a full-time basis

(39,83 hours per week). The position is for two years with an option

to extend up to 5 years (in total). If the applicant meets the relevant

wage requirements and personal qualifications, the salary is based on

remuneration group 13 TV-L of the pay scale for the German public

sector.

For further inquiries, please contact Dr Gabriele Zaffagnini

Postdoc - Protein homeostasis in mammalian oocytes (f/m/x)

Faculty of Mathematics and Natural Sciences

Group Gabriele Zaffagnini | CECAD Research Center



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