Postdoc - in Situ Structural Biology and Biophysics
Vor 5 Tagen
**Our mission as research center**: Discover personalized medical solutions for environmentally triggered diseases to promote a healthier society in a rapidly changing world.
The (HPC) founded and funded by Helmholtz Munich stands for the intelligent fusion of biomedical sciences, engineering and digitization. At HPC, top scientific talents from across the globe work together on the development of novel solutions that make a difference in the prevention, diagnosis and treatment of diseases.
The uses in situ cryo-electron tomography to explore the molecular architecture of actin systems within unperturbed cellular environments, and elucidate the structural principles governing actin functions across scales.
PostDoc - In situ structural biology and biophysics (f/m/x) 101767
Full time
Neuherberg near Munich
Postdocs
**Responsibilities**:
- Lead cryo-electron tomography (cryo-ET) projects on actin-based processes critical for health and disease
- Use the cryo-ET workflow, from cell sample preparation and optimization to imaging and data analysis
- Use/develop computational tools for structure determination and quantitative analysis of cell organization in tomograms
- Help other group members with structural analysis
- Interact with other Helmholtz groups in the fields of artificial intelligence, diabetes or lung disease
- Write scientific publications, research proposals and present results at international conferences
- Help supervise graduate students
Your qualifications
- Excellent PhD in structural biology, bioinformatics, biophysics or related field of science
- Experience with cryo-EM/ET or other structure determination techniques
- Experience with cryo-EM/ET data processing (single-particle analysis/subtomogram averaging)
- Experience with scientific scripting languages (Python and Matlab)
- Fluency in English
Desirable qualifications
- Experience with artificial intelligence and deep learning
- Experience with focused ion beam milling sample preparation
- Experience with fluorescence microscopy
- Experience with molecular modelling
What we offer you
work-life balance flexible working hours & working-time models continuous education and training 30 days annual leave
on-site health management service
home office options on-site nursery & holiday care elder care company pension scheme discounted public transport ticket Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and world-leading research institutions it offers an intellectually stimulating environment.
Provided that the prerequisites are fulfilled, a salary level up to E 13 is possible. Social benefits are based on the collective agreement for the federal public service (TVöD). The position is (initially) limited to three years, under certain circumstances an extension can be arranged.
If you have obtained a university degree abroad, we require further documents from you regarding the recognition of the degree.
Curious? If you have further questions, simply contact Marion Jasnin, +49 89 3187 43896, who will be happy to be of assistance.
Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Helmholtz Pioneer Campus
Ingolstädter Landstraße 1
85764 Neuherberg near Munich
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