Postdoctoral Scientist

The position is open immediately in the research group for neurogenomics and translational myology of of Prof.Dr.Sebahattin Cirak, who is Section Head of Pediatric Neurology and Metabolics at University Ulm is searching immediately for a- Postdoctoral Scientist
- The research laboratory is located within the large pediatric research center of the Department of Pediatrics and Adolescent Medicine (Direktor: Prof. Dr. K.M. Debatin).- The University Hospital Ulm and its employees stand for a modern and high quality patient care, excellent university research and medical education focused on the future as well as apprenticeships in attractive professional fields. The requirements for this are qualified and committed employees.**Your project**:
Investigating cellular and molecular mechanisms of pediatric neurogenetic disorders and muscular dystrophies. Mainly based novel genomics approaches using patient samples and in-vitro models.**Your responsibilities will include**:

- Discovery of novel muscular dystrophy-associated genes molecular mechanisms by latest state-of-the-art OMICs techniques, in particular long-read RNA sequencing and spatial transcriptomics
- Characterization of mouse models to investigate the underlying pathophysiological mechanisms leading to muscular dystrophy
- Development of novel antisense oligonucleotides for exon skipping therapy of Duchenne Muscular Dystrophy in-vitro and mdx mice models
- Development of protein quantification techniques including mass spectrometry
- Working in collaboration with an international team under supervision and leadership of the PI
- Publishing impactful original research papers

**Our offer**:
- **Minimum qualifications**:

- Ph.D in biology and related field and a strong interest in drug development in genetically inherited diseases
- hands-on experience with animal models is desirable
- A solid background in molecular biology is desirable
- Ability to work on multiple project in collaboration with others
- Vertragsart: limited
- Beschäftigungsart: full-time
- Bewerbung bis: 31.03.2024**Are you interested?**- Mit Profil bewerben**Contact**:
Prof. Dr. Sebahattin Cirak
- Sektionsleiter Neuropädiatrie, Stoffwechsel und Sozialpädiatrisches Zentrum
- Universitätsklinik für Kinder
- und Jugendmedizin
- Frauensteige 10, 89075 Ulm
- Germany
- Tel. 49-(0)731-500-57025-
Die Einstellung erfolgt durch die Verwaltung des Klinikums im Namen und im Auftrag des Landes Baden-Württemberg. Personen mit Schwerbehinderung werden bei gleicher Eignung vorrangig eingestellt. Das Universitätsklinikum Ulm strebt die Erhöhung des Frauenanteils in den Bereichen an, in denen sie unterrepräsentiert sind. Entsprechend qualifizierte Frauen werden um ihre Bewerbung gebeten. Eine an die Befristung anschließende Weiterbeschäftigung ist möglich.